Evidence map›Paper›PMID 28855737›Full record

ArticleNature communications2017

Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5.

Sungjun Park, Seungwon Lee, Choong-Gu Lee, Guk Yeol Park, Hyebeen Hong, Jeon-Soo Lee, Young Min Kim, Sung Bae Lee, Daehee Hwang, Youn Soo Choi and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. ETV5 promotes lupus pathogenesis and follicular helper T cell differentiation by inducing osteopontin expression.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Article
  9. Inside-out assembly of viral antigens for the enhanced vaccination.Signal transduction and targeted therapy · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Journal of medical genetics · 2021
    Article
  19. Deletion Timing ofImmune network · 2020
    Article
  20. Ataxin-1 regulates B cell function and the severity of autoimmune experimental encephalomyelitis.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Sungjun ParkDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 73673, Republic of Korea.
Seungwon LeeDivision of Integrative Bioscience and Biotechnology, Pohang University of Science and Technology, Pohang, Gyeongbuk 73673, Republic of Korea.
Choong-Gu LeeAcademy of Immunology and Microbiology, Institute for Basic Science, Pohang, Gyeongbuk 73673, Republic of Korea.ORCID 0000-0002-7977-0408
Guk Yeol ParkDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 73673, Republic of Korea.
Hyebeen HongDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 73673, Republic of Korea.
Jeon-Soo LeeDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 73673, Republic of Korea.
Young Min KimDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 73673, Republic of Korea.
Sung Bae LeeDepartment of Brain &Cognitive Sciences, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu 42988, Republic of Korea.
Daehee HwangCenter for Plant Aging Research, Institute for Basic Science, DGIST, Daegu 42988, Republic of Korea.
Youn Soo ChoiDepartment of Biomedical Sciences, Department of Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
John D FryerDepartment of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA.
Sin-Hyeog ImDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 73673, Republic of Korea.ORCID 0000-0002-3173-1856
Seung-Woo LeeDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 73673, Republic of Korea.
Yoontae LeeDepartment of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 73673, Republic of Korea.
Pohang University of Science and Technology · KRDaegu Gyeongbuk Institute of Science and Technology · KRInstitute for Basic Science · KRJacksonville College · USSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-affinity antibody production through the germinal centre (GC) response is a pivotal process in adaptive immunity. Abnormal development of follicular helper T (T

Indexed as

AutoimmunityAnimalsCell DifferentiationDNA-Binding ProteinsFemaleGerminal CenterHomeostasisImmune ToleranceMaleMice, Inbred C57BLRepressor ProteinsT-Lymphocytes, Helper-InducerTranscription FactorsCic protein, mouseDNA-Binding ProteinsEtv5 protein, mouseRepressor ProteinsTranscription Factors

Identifiers

PMID28855737
PMCPMC5510180
OpenAlexW2736214007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.