ArticleScientific reports2017
MRI and Additive Manufacturing of Nasal Alar Constructs for Patient-specific Reconstruction.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 23 citations in OpenAlex.
- Evaluation of diagnostic accuracy of cone beam computed tomography and multi-detector computed tomography for detection of anatomical variations in rhinoplasty.Head & face medicine · 2024Trial
- Usefulness of T2-Weighted Images with Deep-Learning-Based Reconstruction in Nasal Cartilage.Diagnostics (Basel, Switzerland) · 2023Article
- Anatomy of the nasal latero-lateral cartilage articulation: a micro-MRI study in human specimens.Surgical and radiologic anatomy : SRA · 2022Article
- A photo-crosslinkable cartilage-derived extracellular matrix bioink for auricular cartilage tissue engineering.Acta biomaterialia · 2021Article
- Computational technology for nasal cartilage-related clinical research and application.International journal of oral science · 2020Review
- Subtotal Nasal Reconstruction Using a Custom 3-Dimensional Porous Polyethylene Construct.Plastic and reconstructive surgery. Global open · 2019Article
- Comparison of Micro-Computed Tomography and Clinical Computed Tomography Protocols for Visualization of Nasal Cartilage Before Surgical Planning for Rhinoplasty.JAMA facial plastic surgery · 2019Article
- Rhinoplasty Pre-Surgery Models by Using Low-Dose Computed Tomography, Magnetic Resonance Imaging, and 3D Printing.Dose-response : a publication of International Hormesis SocietyArticle
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Surgical reconstruction of cartilaginous defects remains a major challenge. In the current study, we aimed to identify an imaging strategy for the development of patient-specific constructs that aid in the reconstruction of nasal deformities. Magnetic Resonance Imaging (MRI) was performed on a human cadaver head to find the optimal MRI sequence for nasal cartilage. This sequence was subsequently used on a volunteer. Images of both were assessed by three independent researchers to determine measurement error and total segmentation time. Three dimensionally (3D) reconstructed alar cartilage was then additively manufactured. Validity was assessed by comparing manually segmented MR images to the gold standard (micro-CT). Manual segmentation allowed delineation of the nasal cartilages. Inter- and intra-observer agreement was acceptable in the cadaver (coefficient of variation 4.6-12.5%), but less in the volunteer (coefficient of variation 0.6-21.9%). Segmentation times did not differ between observers (cadaver P = 0.36; volunteer P = 0.6). The lateral crus of the alar cartilage was consistently identified by all observers, whereas part of the medial crus was consistently missed. This study suggests that MRI is a feasible imaging modality for the development of 3D alar constructs for patient-specific reconstruction.
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