Evidence map›Paper›PMID 28855710›Full record

ArticleScientific reports2017

GPR88 is a critical regulator of feeding and body composition in mice.

Jackie Lau, Aitak Farzi, Ronaldo F Enriquez, Yan-Chuan Shi, Herbert Herzog

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  6. Biological psychiatry global open science · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Jackie LauNeuroscience Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, 2010, Australia.
Aitak FarziNeuroscience Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, 2010, Australia.
Ronaldo F EnriquezNeuroscience Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, 2010, Australia.
Yan-Chuan ShiNeuroscience Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, 2010, Australia. y.shi@garvan.org.au.
Herbert HerzogNeuroscience Division, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, 2010, Australia. h.herzog@garvan.org.au.
Garvan Institute of Medical Research · AUMedical University of Graz · ATSt Vincent's Hospital Sydney · AUUNSW Sydney · AU

Funding

Austrian Science Fund FWF J 3814
6 · The paper itself

Abstract

GPR88 is an orphan G-protein-coupled receptor with predominant expression in reward-related areas in the brain. While the lack of GPR88 has been demonstrated to induce behavioral deficits, the potential function of the receptor in the control of food intake and energy balance remains unexplored. In this work, the role of GPR88 in energy homeostasis was investigated in Gpr88

Indexed as

AdiposityAnimalsArcuate Nucleus of HypothalamusBody CompositionCocaine- and Amphetamine-Regulated Transcript ProteinDiet, High-FatEatingEnergy MetabolismFeeding BehaviorFemaleHomeostasisHypothalamusMaleMice, KnockoutNerve Tissue ProteinsNeuropeptide YCocaine- and Amphetamine-Regulated Transcript ProteinGpr88 protein, mouseNerve Tissue ProteinsNeuropeptide YPro-OpiomelanocortinReceptors, G-Protein-Coupled

Identifiers

PMID28855710
PMCPMC5577241
OpenAlexW2747559600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.