ArticleScientific reports2017
Establishment of the most comprehensive ITS2 barcode database to date of the traditional medicinal plant Rhodiola (Crassulacaee).
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Ability to use ITS and rbcL sequencing for determination of the genetic diversity and relationships among olive (3 Biotech · 2025Article
- Comprehensive profiling ofFrontiers in pharmacology · 2025Article
- Single nucleotide polymorphism-based visual identification ofFrontiers in plant science · 2024Article
- Article
- Article
- DNA barcoding: an efficient technology to authenticate plant species of traditional Chinese medicine and recent advances.Chinese medicine · 2022Review
- Comparative analyses of chloroplast genomes from Six Rhodiola species: variable DNA markers identification and phylogenetic relationships within the genus.BMC genomics · 2022Article
- Specification and DNA Barcoding of Thai Traditional Remedy for Chronic Kidney Disease: Pikad Tri-phol-sa-mut-than.Plants (Basel, Switzerland) · 2021Article
- Efficacy of DNA barcode internal transcribed spacer 2 (ITS 2) in phylogenetic study ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2020Article
- Molecular Authentication of the Medicinal Species ofFrontiers in plant science · 2019Article
- DNA barcoding of the genus Nepenthes (Pitcher plant): a preliminary assessment towards its identification.BMC plant biology · 2018Article
- Characterization of the complete chloroplast genome of the traditional medicinal plantsMitochondrial DNA. Part B, Resources · 2018Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The roots and rhizomes of Rhodiola crenulata and R. rosea have been used worldwide as adaptogens for hundreds of years. However, rapid growth in demand has resulted in merchants using other species of Rhodiola as adulterants. Here, we surveyed 518 individuals representing 47 of the 55 species in the genus, including 253 R. crenulata individuals from 16 populations and 98 R. rosea individuals from 11 populations, to evaluate the utility of the internal transcribed spacer 2 (ITS2) barcode for identification of Rhodiola species. We detected six haplotypes in R. crenulata and only one haplotype in R. rosea. An obvious overlap between intra- and inter-specific distance was detected, and the authentication efficacy of ITS2, which was assessed by BLAST1, a nearest distance method, and a tree test, was much lower than in other groups. However, R. crenulata and R. rosea could be exactly identified. Analysis showed that the secondary structure of ITS2 differs in R. crenulata and its closest relatives. Our results demonstrated that both a mini barcode from ITS2 and the structure of ITS2 are effective markers for the identification of R. crenulata and R. rosea. This study represents the most comprehensive database of ITS2 barcodes in Rhodiola to date and will be useful in Rhodiola species identification.
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