Evidence map›Paper›PMID 28855671›Full record

ArticleScientific reports2017

The Genetic Origin of Short Tail in Endangered Korean Dog, DongGyeongi.

DongAhn Yoo, Kwondo Kim, Hyaekang Kim, Seoae Cho, Jin Nam Kim, Dajeong Lim, Seog-Gyu Choi, Bong-Hwan Choi, Heebal Kim

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

DongAhn YooC&K genomics, C-1008, H businesspark, 26, Beobwon-ro 9-gil, Songpa-gu, Seoul, Republic of Korea.ORCID 0000-0003-0033-3721
Kwondo KimC&K genomics, C-1008, H businesspark, 26, Beobwon-ro 9-gil, Songpa-gu, Seoul, Republic of Korea.
Hyaekang KimDepartment of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea.
Seoae ChoC&K genomics, C-1008, H businesspark, 26, Beobwon-ro 9-gil, Songpa-gu, Seoul, Republic of Korea.
Jin Nam KimC&K genomics, C-1008, H businesspark, 26, Beobwon-ro 9-gil, Songpa-gu, Seoul, Republic of Korea.
Dajeong LimNational Institute of Animal Science, RDA, Wanju, 565-851, Republic of Korea.
Seog-Gyu ChoiInstitute of Conservation Gyeongju Donggyeong Dog, Dongguk University, Gyeongju, 780-714, Republic of Korea.
Bong-Hwan ChoiNational Institute of Animal Science, RDA, Wanju, 565-851, Republic of Korea. bhchoi@korea.kr.
Heebal KimC&K genomics, C-1008, H businesspark, 26, Beobwon-ro 9-gil, Songpa-gu, Seoul, Republic of Korea. heebal@snu.ac.kr.
Seoul National University · KRCrystalGenomics (South Korea) · KRNational Institute of Animal Science · KRGyeongju University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The tail of many animal species is responsible for various physiological functions. The functional importance of tail may have brought tail-loss to attention in many evolutionary and developmental studies. To provide a better explanation for the loss of tail, the current study aims to identify the evolutionary history and putative causal variants for the short tail in DongGyeongi (DG), an endangered dog breed, which is also the only dog in Korea that possesses a short tail. Whole genome sequencing was conducted on 22 samples of DG, followed by an investigation of population stratification with 10 other dog breeds. The genotypes, selective sweep and demography of DG were also investigated. As a result, we discovered the unique genetic structure of DG and suggested two possible ways in which the short tail phenotype developed. Moreover, this study suggested that selective sweep genes, ANKRD11 and ACVR2B may contribute to the reduction in tail length, and non-synonymous variant in the coding sequence of T gene and the CpG island variant of SFRP2 gene are the candidate causal variants for the tail-loss.

Indexed as

Endangered SpeciesGenomeActivin Receptors, Type IIAnimalsAnkyrin RepeatApoptosis Regulatory ProteinsDogsFemaleGene ExpressionGenetic SpeciationGenotypeMalePhenotypePhylogenyRepressor ProteinsRepublic of KoreaActivin Receptors, Type IIApoptosis Regulatory ProteinsRepressor Proteins

Identifiers

PMID28855671
PMCPMC5577146
OpenAlexW2748257083

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.