Evidence map›Paper›PMID 28855585›Full record

ArticleScientific reports2017

Nonalcoholic Fatty Liver Disease and Coronary Artery Calcification in a Northern Chinese Population: a Cross Sectional Study.

Rina Wu, Feng Hou, Xiaomin Wang, Yong Zhou, Kai Sun, Youxin Wang, Henghui Liu, Jing Wu, Ruiping Zhao, Jiang Hu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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  17. [Guidelines of prevention and treatment for nonalcoholic fatty liver disease: a 2018 update].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Rina WuDepartment of Cardiology, Central Hospital of Baotou, Baotou, 014040, China.
Feng HouGraduate school, Inner Mongolia Medical University, Hohhot, 010000, China.
Xiaomin WangDepartment of Cardiology, Central Hospital of Baotou, Baotou, 014040, China.
Yong ZhouDepartment of Cardiology, Beijing An Zhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vascular Diseases, Beijing, 100050, China.
Kai SunDepartment of Radiology, Central Hospital of Baotou, Baotou, 014040, China.
Youxin WangBeijing Key Laboratory of Clinical Epidemiology, School of Public Health, Capital Medical University, Beijing, 100069, China.
Henghui LiuBeijing Recdata Technology Co., Ltd, Beijing, 100050, China.
Jing WuBeijing Recdata Technology Co., Ltd, Beijing, 100050, China.
Ruiping ZhaoDepartment of Cardiology, Central Hospital of Baotou, Baotou, 014040, China. ruipingzhao@163.com.
Jiang HuDepartment of Surgery, Central Hospital of Baotou, Baotou, 014040, China. hujiang1961@aliyun.com.
Baotou Central Hospital · CNBeijing Anzhen Hospital · CNCapital Medical University · CNInner Mongolia Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) has become an emerging health issue with a high prevalence in general population. The cross-sectional study was performed to investigate the association between NAFLD and coronary artery calcification (CAC) in individuals from northern city of China. A total of 2345 participants aged ≥40 (1035 men and 1310 women) were selected from the Jidong community of Tangshan city. Liver ultrasonography was used to the diagnosis of NAFLD. A 64-slice CT scanner was used to determine coronary artery calcification score (CACS), with CACS > 0 defined to be the presence of CAC. The risk level of coronary heart disease (CHD) was graded by CACS according to the 4 commonly used thresholds in clinical practice (0, 10, 100, and 400 Agatston units). NAFLD was significantly associated with CAC (crude OR: 1.631, 95% CI: 1.295-2.053, adjusted OR: 1.348, 95% CI: 1.030-1.765). The association between NAFLD and increased risk level of CHD (Crude OR: 1.639 95% CI: 1.303-2.063; adjusted OR: 1.359 95% CI: 1.043-1.770) was observed. The associations between NAFLD and CAC or increased risk level of CHD were significant in female but not in male. Our finding further confirmed the association between NAFLD and CAC, especially in Asian population.

Indexed as

AgedChinaCoronary Artery DiseaseCross-Sectional StudiesFemaleHumansLiverMaleMiddle AgedNon-alcoholic Fatty Liver DiseasePrevalenceTomography, X-Ray ComputedUltrasonographyVascular Calcification

Identifiers

PMID28855585
PMCPMC5577292
OpenAlexW2745540622

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.