Evidence map›Paper›PMID 28855309›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2017

IL-21 Receptor Signaling Is Essential for Optimal CD4

Satyanarayana Swamy Cheekatla, Deepak Tripathi, Sambasivan Venkatasubramanian, Padmaja Paidipally, Elwyn Welch, Amy R Tvinnereim, Roza Nurieva, Ramakrishna Vankayalapati

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. CTLs: Killers of intracellular bacteria.Frontiers in cellular and infection microbiology · 2022
    Review
  7. Article
  8. RNA Sensing ofVaccines · 2020
    Review
  9. A Bovine EntericFrontiers in immunology · 2020
    Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Satyanarayana Swamy CheekatlaDepartment of Pulmonary Immunology, Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX 75708; and.
Deepak TripathiDepartment of Pulmonary Immunology, Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX 75708; and.
Sambasivan VenkatasubramanianDepartment of Pulmonary Immunology, Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX 75708; and.ORCID 0000-0002-9583-4432
Padmaja PaidipallyDepartment of Pulmonary Immunology, Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX 75708; and.
Elwyn WelchDepartment of Pulmonary Immunology, Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX 75708; and.
Amy R TvinnereimDepartment of Pulmonary Immunology, Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX 75708; and.
Roza NurievaDepartment of Immunology, M.D. Anderson Cancer Center, Houston, TX 77030.
Ramakrishna VankayalapatiDepartment of Pulmonary Immunology, Center for Biomedical Research, The University of Texas Health Science Center at Tyler, Tyler, TX 75708; and krishna.vankayalapati@uthct.edu.
The University of Texas Health Science Center at Tyler · USThe University of Texas MD Anderson Cancer Center · US

Funding

IFN-γ independent inhibition of MTB growth in human macrophagesR01AI123310 · NIAID · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI VANKAYALAPATI, RAMAKRISHNA · 2017 to 2020
$1.6M
The role of NK cells in human M. Tuberculosis infectionR01AI054629 · NIAID · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI VANKAYALAPATI, RAMAKRISHNA · 2005 to 2009
$1.3M
T-regs mediated immune responses in LTBI HIV positive individualsR21AI120257 · NIAID · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI VANKAYALAPATI, RAMAKRISHNA · 2015 to 2016
$386k
The role of NK cells in HIV and tuberculosis co-infectionR21AI094692 · NIAID · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI VANKAYALAPATI, RAMAKRISHNA · 2011 to 2012
$383k
The mechanisms of regulatory T-cell expansion in human Mycobacterium tuberculosisR56AI085135 · NIAID · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI VANKAYALAPATI, RAMAKRISHNA · 2010 to 2010
$353k
NIAID NIH HHS R01 AI054629NIAID NIH HHS R01 AI123310NIAID NIH HHS R21 AI094692NIAID NIH HHS R21 AI120257NIAID NIH HHS R56 AI085135
6 · The paper itself

Abstract

In this study, we determined the role of IL-21R signaling in

Indexed as

AnimalsCD4-Positive T-LymphocytesCell ProliferationCells, CulturedFemaleHumansInterferon-gammaLungLymphocyte ActivationMacrophagesMiceMice, Inbred C57BLMice, KnockoutMycobacterium tuberculosisReceptors, Interleukin-21Signal TransductionEomes protein, mouseInterferon-gammaReceptors, Interleukin-21T-Box Domain Proteins

Identifiers

PMID28855309
PMCPMC5636679
OpenAlexW2753763137

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.