Evidence map›Paper›PMID 28855287›Full record

ArticleJournal of neurophysiology2017

GABA transporters regulate tonic and synaptic GABA

Michael Moldavan, Olga Cravetchi, Charles N Allen

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Systematic review of drugs that modify the circadian system's phase-shifting responses to light exposure.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. GABAProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. PdJournal of medicinal chemistry · 2024
    Article
  9. Review
  10. Article
  11. Astrocytes: GABAceptive and GABAergic Cells in the Brain.Frontiers in cellular neuroscience · 2022
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Diurnal properties of tonic and synaptic GABAJournal of neurophysiology · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Michael MoldavanOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, Oregon; and.
Olga CravetchiOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, Oregon; and.
Charles N AllenOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, Oregon; and allenc@ohsu.edu.ORCID 0000-0002-3689-2878
Oregon Health & Science University · US

Funding

CELLULAR ELECTROPHYSIOLOGY OF THE SUPRACHIASMATIC NUCLEIR01NS036607 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ALLEN, CHARLES N · 1998 to 2015
$4.4M
Cellular Electrophysiology of the Suprachiasmatic NucleiR56NS036607 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ALLEN, CHARLES N · 2011 to 2017
$1.1M
NINDS NIH HHS R01 NS036607NINDS NIH HHS R56 NS036607
6 · The paper itself

Abstract

GABA is a principal neurotransmitter in the hypothalamic suprachiasmatic nucleus (SCN) that contributes to intercellular communication between individual circadian oscillators within the SCN network and the stability and precision of the circadian rhythms. GABA transporters (GAT) regulate the extracellular GABA concentration and modulate GABA

Indexed as

Synaptic PotentialsAnimalsAnisolesGABA AntagonistsGABA Plasma Membrane Transport ProteinsGABA Uptake InhibitorsMaleNeuronsNipecotic AcidsOximesPeriod Circadian ProteinsRatsRats, Sprague-DawleyReceptors, GABA-ASuprachiasmatic Nucleus1-(2-(tris(4-methoxyphenyl)methoxy)ethyl)-3-piperidinecarboxylic acidAnisolesGABA AntagonistsGABA Plasma Membrane Transport ProteinsGABA Uptake InhibitorsN-(4,4-diphenyl-3-butenyl)nipecotic acidnipecotic acidNipecotic AcidsNNC 711OximesPer1 protein, ratPeriod Circadian ProteinsReceptors, GABA-AGABAA receptor-mediated currentsGABA transporter 1GABA transporter 3suprachiasmatic nucleus

Identifiers

PMID28855287
PMCPMC5814714
OpenAlexW2753296864

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.