Evidence map›Paper›PMID 28855284›Full record

ArticleG3 (Bethesda, Md.)2017

Whole Genome Sequencing-Based Mapping and Candidate Identification of Mutations from Fixed Zebrafish Tissue.

Nicholas E Sanchez, Breanne L Harty, Thomas O'Reilly-Pol, Sarah D Ackerman, Amy L Herbert, Melanie Holmgren, Stephen L Johnson, Ryan S Gray, Kelly R Monk

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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  9. Dynein/dynactin is necessary for anterograde transport ofProceedings of the National Academy of Sciences of the United States of America · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Nicholas E SanchezDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri 63110.
Breanne L HartyDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri 63110.
Thomas O'Reilly-PolDepartment of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110.
Sarah D AckermanDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri 63110.
Amy L HerbertDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri 63110.
Melanie HolmgrenDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri 63110.
Stephen L JohnsonDepartment of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110.
Ryan S GrayDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri 63110.
Kelly R MonkDepartment of Developmental Biology, Washington University School of Medicine, St. Louis, Missouri 63110 monk@ohsu.edu.
Washington University in St. Louis · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
REGULATION OF ADULT STEM CELLS IN ZEBRAFISHR01GM056988 · NIGMS · WASHINGTON UNIVERSITY · PI JOHNSON, STEPHEN L · 1998 to 2016
$6.0M
Chemical and genetic screens for modulators of nervous system development and myelinationR01HD080601 · NICHD · WASHINGTON UNIVERSITY · PI MONK, KELLY R · 2014 to 2018
$1.6M
Gpr56 is a regulator of glial cell development and myelinationF31NS087801 · NINDS · WASHINGTON UNIVERSITY · PI ACKERMAN, SARAH D · 2014 to 2016
$68k
MOLECULAR CONTROL OF MYELINATING GLIAL CELL DEVELOPMENT BY FBXW7F31NS094004 · NINDS · WASHINGTON UNIVERSITY · PI HARTY, BREANNE LEIGH · 2015 to 2016
$52k
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NCI NIH HHS P30 CA091842NICHD NIH HHS R01 HD080601NIGMS NIH HHS R01 GM056988NINDS NIH HHS F31 NS087801NINDS NIH HHS F31 NS094004
6 · The paper itself

Abstract

As forward genetic screens in zebrafish become more common, the number of mutants that cannot be identified by gross morphology or through transgenic approaches, such as many nervous system defects, has also increased. Screening for these difficult-to-visualize phenotypes demands techniques such as whole-mount

Indexed as

AnimalsChromosome MappingMutationPolymorphism, Single NucleotideTissue FixationWhole Genome SequencingZebrafishfixed tissue sequencinggenetic screenlinkagemappingwhole genome sequencingzebrafish

Identifiers

PMID28855284
PMCPMC5633390
OpenAlexW2753310820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.