Evidence map›Paper›PMID 28855279›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2018

Telomere length dynamics in early life: the blood-and-muscle model.

Sanjeev Sabharwal, Simon Verhulst, George Guirguis, Jeremy D Kark, Carlos Labat, Natalie E Roche, Kristina Martimucci, Krunal Patel, Debra S Heller, Masayuki Kimura and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Telomere Length: Implications for Atherogenesis.Current atherosclerosis reports · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Cells · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 4 countries.

Sanjeev SabharwalDepartment of Orthopedics, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, New Jersey, USA.
Simon VerhulstGroningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, The Netherlands.
George GuirguisDepartment of Obstetrics, Gynecology, and Women's Health, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, New Jersey, USA.
Jeremy D KarkHebrew University-Hadassah School of Public Health and Community Medicine, Jerusalem, Israel.
Carlos LabatINSERM Unité Mixte de Recherche (UMR) S1116, Université de Lorraine, Nancy, France.
Natalie E RocheDepartment of Obstetrics, Gynecology, and Women's Health, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, New Jersey, USA.
Kristina MartimucciDepartment of Obstetrics, Gynecology, and Women's Health, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, New Jersey, USA.
Krunal PatelDepartment of Obstetrics, Gynecology, and Women's Health, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, New Jersey, USA.
Debra S HellerDepartment of Pathology, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, New Jersey, USA.
Masayuki KimuraCenter of Human Development and Aging, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, New Jersey, USA; and.
Donald ChuangCenter of Human Development and Aging, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, New Jersey, USA; and.
Anne ChuangCenter of Human Development and Aging, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, New Jersey, USA; and.
Athanase BenetosINSERM Unité Mixte de Recherche (UMR) S1116, Université de Lorraine, Nancy, France.
Abraham AvivCenter of Human Development and Aging, Rutgers New Jersey Medical School, The State University of New Jersey, Newark, New Jersey, USA; and avivab@njms.rutgers.edu.
Rutgers, The State University of New Jersey · USRutgers New Jersey Medical SchoolCentre Hospitalier Régional et Universitaire de Nancy · FRHebrew University of Jerusalem · ILInserm · FRUniversity Hospital, Newark · USUniversity of Groningen · NL

Funding

Determinants of Leukocyte Telomere Length at BirthR01HD071180 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI AVIV, ABRAHAM, FACTOR-LITVAK, PAM R · 2012 to 2016
$3.3M
Leukocyte Telomere Length and Cardiovascular Disease in Jackson Heart StudyR01HL116446 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI AVIV, ABRAHAM, REINER, ALEXANDER P · 2013 to 2016
$3.1M
NHLBI NIH HHS R01 HL116446NICHD NIH HHS R01 HD071180
6 · The paper itself

Abstract

Telomere length (TL) trajectories in somatic tissues during human growth and development are poorly understood. We examined a blood-and-muscle model during early life, focusing on TL trajectories in leukocytes, representing the highly proliferative hematopoietic system, and skeletal muscle, a minimally proliferative tissue. Leukocyte TL (LTL) and skeletal muscle TL (MTL) were measured in 28 fetuses and 73 children. LTL and MTL were highly variable across individuals (sd: fetal LTL = 0.72 kb, MTL = 0.72 kb; children LTL = 0.81 kb, MTL = 0.82 kb) but were highly correlated within individuals (fetuses,

Indexed as

Models, BiologicalAborted FetusAdolescentAgingChildChild, PreschoolFemaleHumansInfantLeukocytesMaleMuscle, SkeletalTelomere HomeostasisYoung Adultchildrenfetusleukocytes

Identifiers

PMID28855279
PMCPMC5731134
OpenAlexW2753271243

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.