Evidence map›Paper›PMID 28855252›Full record

ArticleThe Journal of biological chemistry2017

The cell envelope-associated phospholipid-binding protein LmeA is required for mannan polymerization in mycobacteria.

Kathryn C Rahlwes, Stephanie A Ha, Daisuke Motooka, Jacob A Mayfield, Lisa R Baumoel, Justin N Strickland, Ana P Torres-Ocampo, Shota Nakamura, Yasu S Morita

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Kathryn C RahlwesFrom the Department of Microbiology, University of Massachusetts, Amherst, MA 01003.
Stephanie A HaFrom the Department of Microbiology, University of Massachusetts, Amherst, MA 01003.
Daisuke Motookathe Department of Infection Metagenomics, Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan.
Jacob A Mayfieldthe Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02445.
Lisa R BaumoelFrom the Department of Microbiology, University of Massachusetts, Amherst, MA 01003.
Justin N StricklandFrom the Department of Microbiology, University of Massachusetts, Amherst, MA 01003.
Ana P Torres-OcampoFrom the Department of Microbiology, University of Massachusetts, Amherst, MA 01003.
Shota Nakamurathe Department of Infection Metagenomics, Research Institute for Microbial Diseases, Osaka University, Osaka 565-0871, Japan.
Yasu S MoritaFrom the Department of Microbiology, University of Massachusetts, Amherst, MA 01003, ymorita@microbio.umass.edu.
University of Massachusetts Amherst · USOsaka University · JPHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integrity of the distinguishing, multilaminate cell envelope surrounding mycobacteria is critical to their survival and pathogenesis. The prevalence of phosphatidylinositol mannosides in the cell envelope suggests an important role in the mycobacterial life cycle. Indeed, deletion of the

Indexed as

Bacterial ProteinsCell MembraneLipopolysaccharidesMannansMannosyltransferasesMycobacterium smegmatisPhospholipidsBacterial ProteinslipoarabinomannanlipomannanLipopolysaccharidesMannansMannosyltransferasesPhospholipidsbacterial geneticscarbohydrate metabolismcell envelopeglycolipidglycosyltransferaselipomannanMycobacterium smegmatisPimE

Identifiers

PMID28855252
PMCPMC5655517
OpenAlexW2752595878

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.