Evidence map›Paper›PMID 28855188›Full record

ArticleAmerican journal of physiology. Renal physiology2017

An excitatory reflex from the superficial peroneal nerve to the bladder in cats.

Michelle Yu, Jamie Uy, Xuewen Jiang, Xing Li, Cameron Jones, Bing Shen, Jicheng Wang, James R Roppolo, William C de Groat, Changfeng Tai

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04000763 (Superficial Peroneal Nerve Neuromodulation for Non-Obstructive Urinary Retention), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04000763 nacompletednot on this mapstarted 2019, after this paper: background citation

Superficial Peroneal Nerve Neuromodulation for Non-Obstructive Urinary Retention

TypeinterventionalSponsorChristopher J Chermansky, MDRan2019 to 2024Enrolled2ConditionsUrinary Retention, Urinary Bladder, UnderactiveArmssuperficial peroneal nerve stimulation
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Superficial peroneal neuromodulation of nonobstructive urinary retention induced by prolonged pudendal afferent activity in cats.American journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Article
  4. Article
  5. Article
  6. Underactive Bladder and Bladder Outlet Procedures in Women.Current bladder dysfunction reports · 2020
    Article
  7. Prolonged nonobstructive urinary retention induced by tibial nerve stimulation in cats.American journal of physiology. Regulatory, integrative and comparative physiology · 2020
    Article
  8. Article
  9. Frequency Dependent Tibial Neuromodulation of Bladder Underactivity and Overactivity in Cats.Neuromodulation : journal of the International Neuromodulation Society · 2018
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Michelle YuDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Jamie UyDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Xuewen JiangDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Xing LiDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Cameron JonesDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Bing ShenDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Jicheng WangDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania.
James R RoppoloDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania; and.
William C de GroatDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania; and.
Changfeng TaiDepartment of Urology, University of Pittsburgh, Pittsburgh, Pennsylvania; cftai@pitt.edu.
University of Pittsburgh · USQilu Hospital of Shandong University · CN

Funding

Parasympathetic and sympathetic mechanisms underlying bladder nociceptionR01DK111382 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BECKEL, JONATHAN M · 2017 to 2020
$1.4M
Neurotransmitter Receptors Involved in Neuromodulation of Bladder OveractivityR01DK102427 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TAI, CHANGFENG · 2014 to 2017
$924k
Central Sites of Action for Bladder NeuromodulationR01DK094905 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TAI, CHANGFENG · 2013 to 2016
$922k
NIDDK NIH HHS R01 DK094905NIDDK NIH HHS R01 DK102427NIDDK NIH HHS R01 DK111382
6 · The paper itself

Abstract

This study in α-chloralose-anesthetized cats discovered an excitatory peroneal nerve-to-bladder reflex. A urethral catheter was used to infuse the bladder with saline and record bladder pressure changes. Electrical stimulation was applied to the superficial peroneal nerve to trigger reflex bladder activity. With the bladder distended at a volume ~90% of bladder capacity, superficial peroneal nerve stimulation (PNS) at 1-3 Hz and threshold (T) intensity for inducing muscle twitching on the posterior thigh induced large-amplitude (40-150 cmH

Indexed as

Electric StimulationAnimalsFemaleMaleMuscle ContractionPeroneal NervePudendal NerveReflexTibial NerveUrinary BladderUrinary Bladder, Overactivecatneuromodulationunderactivity

Identifiers

PMID28855188
PMCPMC5792160
OpenAlexW2753039582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.