ArticleBMC cancer2017
Divergent trends in lung cancer incidence by gender, age and histological type in Estonia: a nationwide population-based study.
Article in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- Lung cancer screening knowledge, opinions and attitudes among healthcare professionals in Estonia prior to national program initiation.Journal of public health research · 2026Article
- Outcomes and Clinical Practices in Follow-Up of Nonmalignant Pulmonary Nodules After Bronchoscopic Biopsy.CHEST pulmonary · 2024Article
- SPP1 facilitates cell migration and invasion by targeting COL11A1 in lung adenocarcinoma.Cancer cell international · 2022Article
- Mortality Trends for Lung Cancer and Smoking Prevalence In Peru.Asian Pacific journal of cancer prevention : APJCP · 2022Article
- Are there differences by sex in lung cancer characteristics at diagnosis? -a nationwide study.Translational lung cancer research · 2021Article
- Impact of COL6A4P2 gene polymorphisms on the risk of lung cancer: A case-control study.PloS one · 2021Article
- Incidence and Survival for Head and Neck Cancers in Estonia, 1996-2016: A Population-Based Study.Clinical epidemiology · 2021Article
- Clustering Trend Changes of Lung Cancer Incidence in Europe via the Growth Mixture Model during 1990-2016.Journal of environmental and public health · 2021Article
- Age and Gender Specific Lung Cancer Incidence and Mortality in Hungary: Trends from 2011 Through 2016.Pathology oncology research : POR · 2021Article
- Spatial and Temporal Analysis of Lung Cancer in Shenzhen, 2008-2018.International journal of environmental research and public health · 2020Article
- Transient impact of paclitaxel on mouse fertility and protective effect of gonadotropin‑releasing hormone agonist.Oncology reports · 2020Article
- Cancer Incidence Trends in the Oil Shale Industrial Region in Estonia.International journal of environmental research and public health · 2020Article
- The Relevance of Gender in Tumor-Influencing Epigenetic Traits.Epigenomes · 2019Review
- Revising Incidence and Mortality of Lung Cancer in Central Europe: An Epidemiology Review From Hungary.Frontiers in oncology · 2019Article
- Procalcitonin Level in Non-Small Cell Lung Cancer Patients among Indonesian Population.Open access Macedonian journal of medical sciences · 2018Article
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Abstract
backgroundLung cancer (LC) is the leading cause of cancer deaths in men and the second most frequent cause of cancer deaths in women in Estonia. The study aimed to analyze time trends in LC incidence and mortality in Estonia over the 30-year period, which included major social, economic and health care transition. The results are discussed in the context of changes in tobacco control and smoking prevalence. Long-term predictions of incidence and mortality are provided.
methodsData for calculating the incidence and mortality rates in 1985-2014 were obtained from the nationwide population-based Estonian Cancer Registry and the Causes of Death Registry. Joinpoint regression was used to analyze trends and estimate annual percentage change (APC) with 95% confidence interval (CI). Nordpred model was used to project future incidence and mortality trends for 2015-2034.
resultsIncidence peaked among men in 1991 and decreased thereafter (APC: -1.5, 95% CI: -1.8; -1.3). A decline was seen for all age groups, except age ≥ 75 years, and for all histological types, except adenocarcinoma and large cell carcinoma. Incidence among women increased overall (APC: 1.6, 95% CI: 1.1; 2.0) and in all age groups and histological types, except small cell carcinoma. Age-standardized incidence rate (world) per 100,000 was 54.2 in men and 12.9 in women in 2014. Changes in mortality closely followed those in incidence. According to our predictions, the age-standardized incidence and mortality rates will continue to decrease in men and reach a plateau in women.
conclusionsThe study revealed divergent LC trends by gender, age and histological type, which were generally consistent with main international findings. Growing public awareness and stricter tobacco control have stimulated overall favorable changes in men, but not yet in women. Large increase in incidence was observed for adenocarcinoma, which in men showed a trend opposite to the overall decline. LC will remain a serious public health issue in Estonia due to a high number of cases during the next decades, related to aging population, and previous and current smoking patterns. National tobacco control policy in Estonia should prioritize preventing smoking initiation and promoting smoking cessation, particularly among women.
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