Evidence map›Paper›PMID 28854896›Full record

ArticleBMC infectious diseases2017

Acute rhabdomyolysis and delayed pericardial effusion in an Italian patient with Ebola virus disease: a case report.

Emanuele Nicastri, Antonio Brucato, Nicola Petrosillo, Gianluigi Biava, Timothy M Uyeki, Giuseppe Ippolito, INMI’s Ebola Team

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Non-traumatic and non-drug-induced rhabdomyolysis.Archives of medical sciences. Atherosclerotic diseases · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Emanuele NicastriNational Institute for Infectious Diseases - INMI - Lazzaro Spallanzani IRCCS, Via Portuense 292, 00149, Rome, Italy. emanuele.nicastri@inmi.it.ORCID 0000-0002-5606-8712
Antonio BrucatoInternal Medicine Ospedale Papa Giovanni XXIII, Bergamo, Italy.
Nicola PetrosilloNational Institute for Infectious Diseases - INMI - Lazzaro Spallanzani IRCCS, Via Portuense 292, 00149, Rome, Italy.
Gianluigi BiavaNational Institute for Infectious Diseases - INMI - Lazzaro Spallanzani IRCCS, Via Portuense 292, 00149, Rome, Italy.
Timothy M UyekiCenters for Disease Control and Prevention, Atlanta, GA, USA.
Giuseppe IppolitoNational Institute for Infectious Diseases - INMI - Lazzaro Spallanzani IRCCS, Via Portuense 292, 00149, Rome, Italy.
INMI’s Ebola Team
Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITCenters for Disease Control and Prevention · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring the 2013-2016 West Africa Ebola virus disease (EVD) epidemic, some EVD patients, mostly health care workers, were evacuated to Europe and the USA. CASE PRESENTATION: In May 2015, a 37-year old male nurse contracted Ebola virus disease in Sierra Leone. After Ebola virus detection in plasma, he was medically-evacuated to Italy. At admission, rhabdomyolysis was clinically and laboratory-diagnosed and was treated with aggressive hydration, oral favipiravir and intravenous investigational monoclonal antibodies against Ebola virus. The recovery clinical phase was complicated by a febrile thrombocytopenic syndrome with pericardial effusion treated with corticosteroids for 10 days and indomethacin for 2 months. No evidence of recurrence is reported.

conclusionsA febrile thrombocytopenic syndrome with pericardial effusion during the recovery phase of EVD appears to be uncommon. Clinical improvement with corticosteroid treatment suggests that an immune-mediated mechanism contributed to the pericardial effusion.

Indexed as

Adrenal Cortex HormonesAdultAmidesAntibodies, MonoclonalEbolavirusHealth PersonnelHemorrhagic Fever, EbolaHumansIndomethacinItalyMalePericardial EffusionPyrazinesRhabdomyolysisSierra LeoneAdrenal Cortex HormonesAmidesAntibodies, MonoclonalfavipiravirIndomethacinPyrazinesEbola Virus DiseasePericardial effusionRhabdomyolysis

Identifiers

PMID28854896
PMCPMC5576302
OpenAlexW2751951925

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.