Evidence map›Paper›PMID 28854882›Full record

ArticleBMC geriatrics2017

A four-domain approach of frailty explored in the Doetinchem Cohort Study.

Sandra H van Oostrom, Daphne L van der A, M Liset Rietman, H Susan J Picavet, Manon Lette, W M Monique Verschuren, Simone R de Bruin, Annemieke M W Spijkerman

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC geriatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06797440 (The Effect of Dual Tasks of Digital Technology on Cognitive Function and Physical Activity in the Older Adults With Cognitive Frailty - A Randomized Controlled Trial), which is not on this map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06797440 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

The Effect of Dual Tasks of Digital Technology on Cognitive Function and Physical Activity in the Older Adults With Cognitive Frailty - A Randomized Controlled Trial

TypeinterventionalSponsorNational Taipei University of Nursing and Health SciencesRan2025 to 2026Enrolled100ConditionsCognitive FrailtyArmsDual tasks of digital technology
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 70 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sandra H van OostromCentre for Nutrition, Prevention and Health Services, National Institute of Public Health and the Environment, P.O. Box 1, 3720, Bilthoven, BA, The Netherlands. sandra.van.oostrom@rivm.nl.
Daphne L van der ACentre for Nutrition, Prevention and Health Services, National Institute of Public Health and the Environment, P.O. Box 1, 3720, Bilthoven, BA, The Netherlands.
M Liset RietmanCentre for Nutrition, Prevention and Health Services, National Institute of Public Health and the Environment, P.O. Box 1, 3720, Bilthoven, BA, The Netherlands.
H Susan J PicavetCentre for Nutrition, Prevention and Health Services, National Institute of Public Health and the Environment, P.O. Box 1, 3720, Bilthoven, BA, The Netherlands.
Manon LetteCentre for Nutrition, Prevention and Health Services, National Institute of Public Health and the Environment, P.O. Box 1, 3720, Bilthoven, BA, The Netherlands.
W M Monique VerschurenCentre for Nutrition, Prevention and Health Services, National Institute of Public Health and the Environment, P.O. Box 1, 3720, Bilthoven, BA, The Netherlands.
Simone R de BruinCentre for Nutrition, Prevention and Health Services, National Institute of Public Health and the Environment, P.O. Box 1, 3720, Bilthoven, BA, The Netherlands.
Annemieke M W SpijkermanCentre for Nutrition, Prevention and Health Services, National Institute of Public Health and the Environment, P.O. Box 1, 3720, Bilthoven, BA, The Netherlands.
National Institute for Public Health and the Environment · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccumulation of problems in physical, psychological, cognitive, or social functioning is characteristic for frail individuals. Using a four-domain approach of frailty, this study explored how sociodemographic and lifestyle factors, life events and health are associated with frailty.

methodsThe study sample included 4019 men and women (aged 40-81 years) examined during the fifth round (2008-2012) of the Doetinchem Cohort Study. Four domains of frailty were considered: physical (≥4 of 8 criteria: unintentional weight loss, exhaustion, strength, perceived health, walking, balance, hearing and vision impairments), psychological (2 criteria: depressive symptoms, mental health), cognitive (<10th percentile on global cognitive functioning), and social frailty (≥2 of 3 criteria: loneliness, social support, social participation). Logistic regression was used to study the cross-sectional association of sociodemographic factors, lifestyle, life events and chronic diseases with frailty domains.

resultsAbout 17% of the population was frail on one or more domains. Overlap between the frailty domains was limited since 82% of the frail population was frail on one domain only. Low educated respondents were at higher risk of being psychologically and socially frail. Having multiple diseases was associated with a higher risk of being physically and psychologically frail. Being physically active was consistently associated with a lower risk of frailty on each of the four domains. Short or long sleep duration was associated with a higher risk of being physically, psychologically, and socially frail.

conclusionsSociodemographic factors, lifestyle and multimorbidity contributed differently to the four frailty domains. It is important to consider multiple frailty domains since this helps to identify different groups of frail people, and as such to provide tailored care and support. Lifestyle factors including physical activity, smoking and sleep duration were associated with multiple domains of frailty.

Indexed as

FrailtyAdultAgedAged, 80 and overChronic DiseaseCohort StudiesFemaleFrail ElderlyHealth StatusHumansLife Change EventsLife StyleMaleMental HealthMiddle AgedNetherlandsFrailtyLifestyleMultidimensionalPhysical activityProspective cohortSleep

Identifiers

PMID28854882
PMCPMC5577839
OpenAlexW2751677606

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.