Evidence map›Paper›PMID 28853979›Full record

Trial reportJournal of adolescent and young adult oncology2019

The Effect of Atorvastatin on Vascular Function and Structure in Young Adult Survivors of Childhood Cancer: A Randomized, Placebo-Controlled Pilot Clinical Trial.

Kara L Marlatt, Julia Steinberger, Kyle D Rudser, Donald R Dengel, Karim T Sadak, Jill L Lee, Anne H Blaes, Daniel A Duprez, Joanna L Perkins, Julie A Ross and 1 more

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of adolescent and young adult oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Drug repurposing for cancer therapy.Signal transduction and targeted therapy · 2024
    Review
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  11. Pleiotropic effects of statins: A focus on cancer.Biochimica et biophysica acta. Molecular basis of disease · 2020
    Review
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  13. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Kara L Marlatt1Pennington Biomedical Research Center, Baton Rouge, Louisiana.
Julia Steinberger2Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota.
Kyle D Rudser3Division of Biostatistics, School of Public Health, and Clinical and Translational Science Institute, University of Minnesota, Minneapolis, Minnesota.
Donald R Dengel2Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota.
Karim T Sadak2Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota.
Jill L Lee2Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota.
Anne H Blaes5Cancer and Blood Disorders Program, Children's Hospitals and Clinics of Minnesota, Minneapolis, Minnesota.
Daniel A Duprez6Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota.
Joanna L Perkins5Cancer and Blood Disorders Program, Children's Hospitals and Clinics of Minnesota, Minneapolis, Minnesota.
Julie A Ross2Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota.
Aaron S Kelly2Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota.
University of Minnesota Medical Center · USChildren’s Minnesota - St. Paul Hospital · USPennington Biomedical Research Center · USUniversity of Minnesota · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
Training in Obesity ResearchT32DK064584 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI CORBY K MARTIN, Christopher D Morrison · 2003 to 2026
$5.3M
NCATS NIH HHS UL1 TR000114NIDDK NIH HHS T32 DK064584NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cancer SurvivorsAdolescentAdultAtherosclerosisAtorvastatinCarotid ArteriesChildChild, PreschoolDouble-Blind MethodEndothelium, VascularFemaleFollow-Up StudiesHumansHydroxymethylglutaryl-CoA Reductase InhibitorsLymphoma, Non-HodgkinMaleAtorvastatinHydroxymethylglutaryl-CoA Reductase Inhibitorscardiovascularstatintrialvascular

Identifiers

PMID28853979
PMCPMC6689188
OpenAlexW2752309293

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.