Evidence map›Paper›PMID 28853919›Full record

ReviewAnnual review of genetics2017

Regeneration Genetics.

Chen-Hui Chen, Kenneth D Poss

Abstract readReview
In one paragraph

Review in Annual review of genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. DNA Methylation Dynamics inBiomolecules · 2026
    Article
  2. Article
  3. Mammalian organ regeneration in spiny mice.Journal of muscle research and cell motility · 2023
    Review
  4. Article
  5. Article
  6. Voltage-gated sodium channelProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Damage-responsive elements inGenome research · 2018
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Chen-Hui ChenInstitute of Cellular and Organismic Biology, Academia Sinica, Taipei 11529, Taiwan; email: chcchen@gate.sinica.edu.tw.
Kenneth D PossDepartment of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710, USA; email: kenneth.poss@duke.edu.

Funding

Regulation of Myocardial Regeneration in ZebrafishR01HL081674 · NHLBI · DUKE UNIVERSITY · PI POSS, KENNETH D · 2005 to 2019
$6.6M
Regulation of Appendage Regeneration in ZebrafishR01GM074057 · NIGMS · DUKE UNIVERSITY · PI POSS, KENNETH D · 2006 to 2017
$3.7M
Identification and application of regulatory elements for heart regenerationR01HL136182 · NHLBI · DUKE UNIVERSITY · PI BLACK, BRIAN L, POSS, KENNETH D · 2017 to 2020
$3.1M
Regulation of the Epicardial Injury Response During Heart Regeneration in ZebrafishR01HL131319 · NHLBI · DUKE UNIVERSITY · PI POSS, KENNETH D · 2016 to 2019
$1.6M
Regulation of glial bridging during spinal cord regeneration in zebrafishR21NS096617 · NINDS · DUKE UNIVERSITY · PI POSS, KENNETH D · 2017 to 2018
$437k
NHLBI NIH HHS R01 HL081674NHLBI NIH HHS R01 HL131319NHLBI NIH HHS R01 HL136182NIGMS NIH HHS R01 GM074057NINDS NIH HHS R21 NS096617
6 · The paper itself

Abstract

Understanding how and why animals regenerate complex tissues has the potential to transform regenerative medicine. Here we present an overview of genetic approaches that have recently been applied to dissect mechanisms of regeneration. We describe new advances that relate to central objectives of regeneration biologists researching different tissues and species, focusing mainly on vertebrates. These objectives include defining the cellular sources and key cell behaviors in regenerating tissue, elucidating molecular triggers and brakes for regeneration, and defining the earliest events that control the presence of these molecular factors.

Indexed as

AnimalsAnimals, Genetically ModifiedBacterial ProteinsCaudataGenes, ReporterGenomicsGreen Fluorescent ProteinsHumansLuminescent ProteinsMolecular ImagingPromoter Regions, GeneticRed Fluorescent ProteinRegenerationRegenerative MedicineReverse GeneticsSignal TransductionBacterial ProteinsCyan Fluorescent ProteinGreen Fluorescent ProteinsLuminescent ProteinsRed Fluorescent Proteinyellow fluorescent protein, Bacteriablastemageneticsimagingregenerationsalamanderszebrafish

Identifiers

PMID28853919
PMCPMC5705327

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.