Evidence map›Paper›PMID 28853029›Full record

Trial reportSports medicine (Auckland, N.Z.)2018

Effect of High-Intensity Interval Training on Fitness, Fat Mass and Cardiometabolic Biomarkers in Children with Obesity: A Randomised Controlled Trial.

Katrin A Dias, Charlotte B Ingul, Arnt E Tjønna, Shelley E Keating, Sjaan R Gomersall, Turid Follestad, Mansoureh S Hosseini, Siri M Hollekim-Strand, Torstein B Ro, Margrete Haram and 5 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Sports medicine (Auckland, N.Z.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01991106 (A Multi-centre Randomized Controlled Trial Examining the Effects of High Intensity Interval Training on Cardio-metabolic Outcomes in Obese Children and Adolescents), which is not on this map. Cited by 74 papers, 24 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 24 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01991106 nacompletednot on this map

A Multi-centre Randomized Controlled Trial Examining the Effects of High Intensity Interval Training on Cardio-metabolic Outcomes in Obese Children and Adolescents

TypeinterventionalSponsorNorwegian University of Science and TechnologyRan2013 to 2017Enrolled100ConditionsObesityArmsHigh intensity interval training, Moderate intensity continuous training, Nutritional advice
3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 24 syntheses or guidelines pooled it, 147 citations in OpenAlex.

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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Katrin A DiasSchool of Human Movement and Nutrition Sciences, The University of Queensland, St Lucia, Brisbane, QLD, 4072, Australia.
Charlotte B IngulDepartment of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Arnt E TjønnaDepartment of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Shelley E KeatingSchool of Human Movement and Nutrition Sciences, The University of Queensland, St Lucia, Brisbane, QLD, 4072, Australia.
Sjaan R GomersallSchool of Health and Rehabilitation Sciences, The University of Queensland, St Lucia, Brisbane, QLD, Australia.
Turid FollestadDepartment of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Mansoureh S HosseiniDepartment of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Siri M Hollekim-StrandDepartment of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Torstein B RoDepartment of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
Margrete HaramDepartment of Radiology and Nuclear Medicine, Trondheim University Hospital, Trondheim, Norway.
Else Marie HuuseDepartment of Radiology and Nuclear Medicine, Trondheim University Hospital, Trondheim, Norway.
Peter S W DaviesChildren's Nutrition Research Centre, The University of Queensland, Brisbane, QLD, Australia.
Peter A CainHeart Care Partners, The Wesley Hospital, Brisbane, QLD, Australia.
Gary M LeongInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia.
Jeff S CoombesSchool of Human Movement and Nutrition Sciences, The University of Queensland, St Lucia, Brisbane, QLD, 4072, Australia. jcoombes@uq.edu.au.
University of Queensland · AUNorwegian University of Science and Technology · NOSt Olav's University Hospital · NOCentral Norway Regional Health Authority · NOQueensland Children’s Hospital · AUWesley Hospital · AU

Funding

St Olav's Hospital and The Norwegian University of Science and Technology #9527The Wesley and St Andrew's Research Institute #2014-01
6 · The paper itself

Abstract

backgroundPaediatric obesity significantly increases the risk of developing cardiometabolic diseases across the lifespan. Increasing cardiorespiratory fitness (CRF) could mitigate this risk. High-intensity interval training (HIIT) improves CRF in clinical adult populations but the evidence in paediatric obesity is inconsistent.

objectivesThe objectives of this study were to determine the efficacy of a 12-week, HIIT intervention for increasing CRF and reducing adiposity in children with obesity.

methodsChildren with obesity (n = 99, 7-16 years old) were randomised into a 12-week intervention as follows: (1) HIIT [n = 33, 4 × 4-min bouts at 85-95% maximum heart rate (HR

resultsHIIT stimulated significant increases in relative [Formula: see text] compared with MICT (+3.6 mL/kg/min, 95% CI 1.1-6.0, P = 0.004) and the nutrition intervention (+5.4 mL/kg/min, 95% CI 2.9-7.9, P = 0.001). However, the intervention had no significant effect on visceral and subcutaneous adipose tissue, whole body composition or cardiometabolic biomarkers (P > 0.05).

conclusionA 12-week, HIIT intervention was highly effective in increasing cardiorespiratory fitness when compared with MICT and nutrition interventions. While there were no concomitant reductions in adiposity or blood biomarkers, the cardiometabolic health benefit conferred through increased CRF should be noted. CLINICAL TRIALS REGISTRATION NUMBER: Clinicaltrials.gov; NCT01991106.

Indexed as

Cardiorespiratory FitnessHigh-Intensity Interval TrainingAdiposityAdolescentBiomarkersCardiovascular DiseasesChildExercise TherapyFemaleHumansMetabolic SyndromeOxygen ConsumptionPediatric ObesitySexual MaturationTime FactorsTreatment OutcomeBiomarkers

Identifiers

PMID28853029
OpenAlexW2753869748

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.