ArticleEuropean journal of pediatrics2017
Epidemiological factors related to hospitalization due to influenza in children below 6 months of age.
Article in European journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Twins with at least one with CHD and their immunisation status in direct comparison-are both twins complying with the German immunisation recommendations?Cardiovascular diagnosis and therapy · 2024Article
- Effectiveness of cocoon strategy vaccination on prevention of influenza-like illness in young infants.Human vaccines & immunotherapeutics · 2024Article
- Hospitalization of Children Aged <5 Years Due to Influenza: Study Based on the National Hospitalization RegistryChildren (Basel, Switzerland) · 2022Article
- Influenza vaccination among caregivers and household contacts of children with congenital heart disease before and during COVID-19 pandemic.Journal of paediatrics and child health · 2022Article
- Influenza hospitalizations in children under 1 year old in Spain: the importance of maternal immunization.Human vaccines & immunotherapeutics · 2021Article
- Non-Toxic Virucidal Macromolecules Show High Efficacy Against Influenza Virus Ex Vivo and In Vivo.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021Article
- A severe influenza season in Austria and its impact on the paediatric population: mortality and hospital admission rates, november 2017 - march 2018.BMC public health · 2020Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to address the epidemiological factors associated to hospital admissions due to influenza in infants younger than 6 months. A case-control study was performed in a tertiary hospital in Spain. Cases were infants under 6 months of age without comorbidities who were admitted due to influenza between October 2010 and March 2015. Controls were healthy infants younger than 6 months who were hospitalized due to non-respiratory illness or non-infectious diseases (urinary tract infection was included as controls). Data were retrospectively collected from medical records and phone interviews. A total of 88 cases and 122 controls we included. From univariate analysis, differences were found in relation to maternal age (43.1 ± 4.95 vs 32 ± 5.3), paternal age (37 ± 6.4 vs 34.5 ± 6.1), having siblings (79 vs 24%), siblings below 4 years old (54 vs 15%), and having vaccinated grandparents (18 vs 39%) (p < 0.05). After logistic regression, having vaccinated grandparents was an independent protective factor (OR 0.22 [CI95%; 0.05-0.91]), while having siblings was a risk factor (OR 15.8 [CI95% 3.15-79.5]). Vaccination during pregnancy was highly uncommon (3.5 vs 8.3%; p = 0.3).
conclusionThis study underlines the importance of increasing influenza immunization among household contacts of infants below 6 months to prevent their influenza admission. What is Known: • Infants younger than 6 months old are considered a high-risk population. • Vaccination against influenza is not licensed in infants below 6 months. What is New: • Increasing vaccination coverage in elderly people could reduce infants' hospitalization rates. • Cocoon immunization strategy may reduce the admission of infants.
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