Evidence map›Paper›PMID 28852729›Full record

ArticleAfrican journal of traditional, complementary, and alternative medicines : AJTCAM2016

HEXANE EXTRACT OF

Chidinma A Okolo, Vincent C Ejere, Christian O Chukwuka, Ihechiluru I Ezeigbo, Daniel D Nwibo, Augustine N Okorie

Abstract read
In one paragraph

Article in African journal of traditional, complementary, and alternative medicines : AJTCAM, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. The GenusPharmaceuticals (Basel, Switzerland) · 2023
    Review
  2. Herbal Medicines Targeting the ImprovedEvidence-based complementary and alternative medicine : eCAM · 2021
    Review
  3. Effect of feed supplementation ofTranslational animal science · 2020
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chidinma A OkoloPhysiology Unit, Department of Zoology and Environmental Biology, Faculty of Biological Sciences, University of Nigeria, Nsukka, Enugu State. 410001, Nigeria.
Vincent C EjerePhysiology Unit, Department of Zoology and Environmental Biology, Faculty of Biological Sciences, University of Nigeria, Nsukka, Enugu State. 410001, Nigeria.
Christian O ChukwukaDepartment of Biology and Biotechnology, Federal University Ndufu-Alike Ikwo, PMB 1010 Abakiliki, Ebonyi State Nigeria.
Ihechiluru I EzeigboDepartment of Veterinary Physiology, Biochemistry and Pharmacology, Michael Okpara University of Agriculture, Umudike, PMB 7267 Umuahia, Nigeria.
Daniel D NwiboDepartment of Pure and Industrial Chemistry, University of Nigeria, Nsukka 410001, Nigeria.
Augustine N OkorieDepartment of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka 410001, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe fruit extract of MATERIALS AND

methodsSub-toxic doses between 400 and 1600mg/kg were orally administered sub-chronically to alloxan-induced diabetic rats for 15 days and compared to glibenclamide (2.5mg/kg). The glycaemia levels, body weights, lipid profile, blood urea, creatinine and liver enzyme levels were measured. Basic histology of the pancreatic tissue was also performed to examine the effects on the pancreas as possible mechanistic lead.

resultsOral acute dosing of

conclusionOur findings portend that D. edulis hexane fruit extract possesses hypoglycaemic and hypolipidaemic activities as well as restoration of the pancreatic architecture without any obvious untoward hepatic damages, suggesting that its use in the management of the diabetes may be valid.

Indexed as

AlloxanAnimalsBlood GlucoseBurseraceaeCholesterolDiabetes Mellitus, ExperimentalFemaleFruitHexanesHumansHypoglycemic AgentsHypolipidemic AgentsMaleMiceNigeriaPhytotherapyAlloxanBlood GlucoseCholesterolHexanesHypoglycemic AgentsHypolipidemic AgentsPlant ExtractsTriglyceridesanti-diabeticDacryodes edulisdiabeteshypolipidaemic

Identifiers

PMID28852729
PMCPMC5566136

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.