ReviewBioMed research international2017
Predictive Value of CTA Spot Sign on Hematoma Expansion in Intracerebral Hemorrhage Patients.
Review in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Imaging predictors of hemorrhagic progression of a contusion after traumatic brain injury: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Is four-dimensional CT angiography as effective as digital subtraction angiography in the detection of the underlying causes of intracerebral haemorrhage: a systematic review.Neuroradiology · 2020Pooled it
- Spot Sign in Secondary Intraventricular Hemorrhage Predicts Early Neurological Decline.Clinical neuroradiology · 2020Trial
- Review
- Current evidence and future directions for prophylactic anticoagulation therapy after severe spontaneous intracerebral hemorrhage: a narrative review.Journal of intensive medicine · 2026Review
- Monocyte-to-high-density lipoprotein cholesterol ratio predicts hematoma expansion and poor outcomes in patients with spontaneous intracerebral hemorrhage.BMC neurology · 2026Article
- Application of deep learning and radiomics in the prediction of hematoma expansion in intracerebral hemorrhage: a fully automated hybrid approachDiagnostic and interventional radiology (Ankara, Turkey) · 2024Article
- Ferroptosis and mitochondrial dysfunction in acute central nervous system injury.Frontiers in cellular neuroscience · 2023Review
- A predictive nomogram for intracerebral hematoma expansion based on non-contrast computed tomography and clinical features.Neuroradiology · 2022Article
- Comparison of Radiomic Models Based on Different Machine Learning Methods for Predicting Intracerebral Hemorrhage Expansion.Clinical neuroradiology · 2022Article
- Identifying risk factors of intracerebral hemorrhage stability using explainable attention model.Medical & biological engineering & computing · 2022Article
- Quantitative CT radiomics-based models for prediction of haematoma expansion and poor functional outcome in primary intracerebral haemorrhage.European radiology · 2021Article
- Noncontrast computer tomography-based radiomics model for predicting intracerebral hemorrhage expansion: preliminary findings and comparison with conventional radiological model.European radiology · 2020Article
- Correlation between Spot Sign and Intracranial Hemorrhage Expansion on Dual-Phase CT Angiography.Diagnostics (Basel, Switzerland) · 2019Article
- The risk factors and prognosis of delayed perihematomal edema in patients with spontaneous intracerebral hemorrhage.CNS neuroscience & therapeutics · 2019Article
- The Role of Serum Calcium Level in Intracerebral Hemorrhage Hematoma Expansion: Is There Any?Neurocritical care · 2019Review
- Active Reperfusion Hemorrhage during Thrombectomy: Angiographic Findings and Real-Time Correlation with the CT "Spot Sign".Interventional neurology · 2018Article
- Comparison of CT black hole sign and other CT features in predicting hematoma expansion in patients with ICH.Journal of neurology · 2018Article
- EIT Imaging of Intracranial Hemorrhage in Rabbit Models Is Influenced by the Intactness of Cranium.BioMed research international · 2018Article
- Prediction of Hematoma Expansion in Hypertensive Intracerebral Hemorrhage by a Radiomics Nomogram.Pakistan journal of medical sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hematoma expansion (HE) occurs in approximately one-third of patients with intracerebral hemorrhage and leads to high rates of mortality and morbidity. Currently, contrast extravasation within hematoma, termed the spot sign on computed tomography angiography (CTA), has been identified as a strong independent predictor of early hematoma expansion. Past studies indicate that the spot sign is a dynamic entity and is indicative of active hemorrhage. Furthermore, to enhance the spot sign's accuracy of predicting HE, spot parameters observed on CTA or dynamic CTA were used for its quantification. In addition, spot signs detected on multiphase CTA and dynamic CTA are shown to have higher sensitivity and specificity when compared with simple standardized spot sign detection in recent studies. Based on the spot sign, novel methods such as leakage sign and rate of contrast extravasation were explored to redefine HE prediction in combination with clinical characteristics and spot sign on CTA to assist clinical judgment. The spot sign is an accepted independent predictor of active hemorrhage and is used in both secondary intracerebral hemorrhage and the process of surgical assessment for hemorrhagic risk in patients with ischemic stroke. Spot sign predicts patients at high risk for hematoma expansion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.