Evidence map›Paper›PMID 28852530›Full record

ArticleGynecologic oncology research and practice2017

Multidisciplinary approach to manage antenatally suspected placenta percreta: updated algorithm and patient outcomes.

Paula S Lee, Samantha Kempner, Michael Miller, Jennifer Dominguez, Chad Grotegut, Jessie Ehrisman, Rebecca Previs, Laura J Havrilesky, Gloria Broadwater, Sarah C Ellestad and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Gynecologic oncology research and practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 40 citations in OpenAlex.

  1. The utility of serum markers in the conservative management of placenta accreta spectrum (PAS) by leaving the placenta in situ in women with high-grade PAS.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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  7. A comparison of antenatally and intraoperatively diagnosed cases of placenta accreta spectrumJournal of the Turkish German Gynecological Association · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Paula S LeeDepartment of Obstetrics and Gynecology, Duke University Hospital, Durham, North Carolina 27710 USA.ORCID 0000-0003-3524-0058
Samantha KempnerDepartment of Obstetrics and Gynecology, Duke University Hospital, Durham, North Carolina 27710 USA.
Michael MillerDepartment of Interventional Radiology, Duke University Hospital, Durham, USA.
Jennifer DominguezDepartment of Anesthesiology, Duke University Hospital, Durham, USA.
Chad GrotegutDepartment of Obstetrics and Gynecology, Duke University Hospital, Durham, North Carolina 27710 USA.
Jessie EhrismanDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Duke University Hospital, Durham, USA.
Rebecca PrevisDepartment of Obstetrics and Gynecology, Duke University Hospital, Durham, North Carolina 27710 USA.
Laura J HavrileskyDepartment of Obstetrics and Gynecology, Duke University Hospital, Durham, North Carolina 27710 USA.
Gloria BroadwaterCancer Statistical Center, Duke Cancer Institute, Durham, USA.
Sarah C EllestadDepartment of Obstetrics and Gynecology, Duke University Hospital, Durham, North Carolina 27710 USA.
Angeles Alvarez SecordDepartment of Obstetrics and Gynecology, Duke University Hospital, Durham, North Carolina 27710 USA.
Duke University Hospital · USDuke Institute for Health Innovation · USDuke Cancer Institute

Funding

INTEGRATED TRAINING IN ANESTHESIOLOGY RESEARCHT32GM008600 · NIGMS · DUKE UNIVERSITY · PI Miriam Treggiari · 1996 to 2026
$6.6M
NIGMS NIH HHS T32 GM008600
6 · The paper itself

Abstract

backgroundDue to the significant morbidity and mortality associated with placenta percreta, alternative management options are needed. Beginning in 2005, our institution implemented a multidisciplinary strategy to patients with suspected placenta percreta. The purpose of this study is to present our current strategy, maternal morbidity and outcomes of patients treated by our approach.

methodsFrom 2005 to 2014, a retrospective cohort study of patients with suspected placenta percreta at an academic tertiary care institution was performed. Treatment modalities included immediate hysterectomy at the time of cesarean section (CHYS), planned delayed hysterectomy (interval hysterectomy 6 weeks after delivery) (DH), and fertility sparing (uterine conservation) (FS). Prognostic factors of maternal morbidity were identified from medical records. Complications directly related to interventional procedures and DH was recorded. Descriptive statistics were utilized.

resultsOf the 21 patients with suspected placenta percreta, 7 underwent CHYS, 13 underwent DH, and 1 had FS with uterine preservation. Of the 20 cases that underwent hysterectomy, final pathology showed 11 increta, 7 percreta, and 2 inconclusive. 19/20 cases underwent interventional radiology (IR) procedures. Selective embolization was utilized in 14 cases (2/7 CHYS; 12/13 DH). The median time from cesarean section (CS) to DH was 41 [26-68] days. There were no cases of emergent hysterectomy, delayed hemorrhage, or sepsis in the DH group. Both estimated blood loss and number of packed red blood cell transfusions were significantly higher in the CHYS group. 3/21 cases required massive transfusion (2 CHYS, 1 FS) with median total blood product transfusion of 13 units [12-15]. The four IR-related complications occurred in the DH group. Incidence of postoperative complications was similar between both groups. Median hospital length of stay (LOS) after CHYS was 4 days [3-8] compared to DH cohort: 7 days [3-33] after CS and 4 days [1 -10] after DH. The DH cohort had a higher rate of hospital readmission of 54% (7/13) compared to 14% (1/7) CHYS, most commonly due to pain. There were no maternal deaths.

conclusionThis multidisciplinary strategy may appear feasible; however, further investigation is warranted to evaluate the effectiveness of alternative approaches to cesarean hysterectomy in cases of morbidly adherent placenta.

Indexed as

Conservative management of placenta percretaDelayed hysterectomyPostpartum hemorrhageUterine artery embolization

Identifiers

PMID28852530
PMCPMC5567476
OpenAlexW2749796092

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.