ReviewGastroenterology report2017
Variceal bleeding in cirrhotic patients.
Review in Gastroenterology report, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05199038 (Comparison of 2 Days Versus 5 Days of Octreotide After Endoscopic Therapy in Preventing Early Esophageal Varices Rebleed), which is not on this map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparison of 2 Days Versus 5 Days of Octreotide After Endoscopic Therapy in Preventing Early Esophageal Varices Rebleed: A Randomized Controlled Study
Who cites it
18 citing papers in PubMed, 59 citations in OpenAlex.
- Effects of Preoperative Oral Carbohydrate on Cirrhotic Patients under Endoscopic Therapy with Anesthesia: A Randomized Controlled Trial.BioMed research international · 2021Trial
- A primer on the imaging approach to acute gastrointestinal bleeding.Abdominal radiology (New York) · 2026Review
- Preliminary research on the effectiveness and safety of metal clip-assisted endoscopic variceal ligation in the treatment of gastric varices.Therapeutic advances in gastroenterology · 2026Article
- Review
- Thrombocytopenia and Grading of Esophageal Varices in Patients With Chronic Liver Disease.Cureus · 2024Article
- Efficacy and safety of variceal embolization for primary prophylaxis in cirrhosis patients with challenges in standard treatments: preliminary results.Frontiers in medicine · 2024Article
- Pathophysiology and management of bleeding and thrombosis in patients with liver disease.International journal of laboratory hematology · 2022Review
- Practical Strategies Related to the Application of Balloon Tamponade Therapy in Acute Variceal Bleeding.Critical care explorations · 2022Article
- Associations Between Endoscopic Primary Prophylaxis and Rebleeding in Liver Cirrhosis Patients with Esophagogastric Variceal Bleeding.Frontiers in surgery · 2022Article
- Accelerated balloon-retrograde transvenous obliteration (BRTO): an effective tool in the Arsenal against isolated gastric varices (IGV).BMJ case reports · 2021Article
- LigaSure versus monopolar cautery for recipient hepatectomy in liver transplantation: a propensity score-matched analysis.Annals of translational medicine · 2021Article
- Review
- Clinical significance of isolated gastric varices in liver cirrhotic patients: A single-referral-centre retrospective cohort study.JGH open : an open access journal of gastroenterology and hepatology · 2020Article
- Emergent Transjugular Intrahepatic Portosystemic Shunt Creation in Acute Variceal Bleeding.Seminars in interventional radiology · 2020Review
- Towards definitions of time-sensitive conditions in prehospital care.Scandinavian journal of trauma, resuscitation and emergency medicine · 2020Article
- Lnc-TCL6 is a potential biomarker for early diagnosis and grade in liver-cirrhosis patients.Gastroenterology report · 2019Article
- Parallel transjugular intrahepatic portosystemic shunt with ViatorrWorld journal of hepatology · 2019Article
- Endovascular Treatment for Variceal Hemorrhage: TIPS, BRTO, and Combined Approaches.Seminars in interventional radiology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Variceal bleeding is one of the major causes of death in cirrhotic patients. The management during the acute phase and the secondary prophylaxis is well defined. Recent recommendations (2015 Baveno VI expert consensus) are available and should be followed for an optimal management, which must be performed as an emergency in a liver or general intensive-care unit. It is based on the early administration of a vasoactive drug (before endoscopy), an antibiotic prophylaxis and a restrictive transfusion strategy (hemoglobin target of 7 g/dL). The endoscopic treatment is based on band ligations. Sclerotherapy should be abandoned. In the most severe patients (Child Pugh C or B with active bleeding during initial endoscopy), transjugular intrahepatic portosystemic shunt (TIPS) should be performed within 72 hours after admission to minimize the risk of rebleeding. Secondary prophylaxis is based on the association of non-selective beta-blockers (NSBBs) and repeated band ligations. TIPS should be considered when bleeding reoccurs in spite of a well-conducted secondary prophylaxis or when NSBBs are poorly tolerated. It should also be considered when bleeding is refractory. Liver transplantation should be discussed when bleeding is not controlled after TIPS insertion and in all cases when liver function is deteriorated.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.