ArticleGastroenterology report2017
Perioperative use of immunosuppressive medications in patients with Crohn's disease in the new "biological era".
Article in Gastroenterology report, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- The Impact of Perioperative Immunosuppression on Post-surgical Outcomes in Patients with Inflammatory Bowel Disease.Digestive diseases and sciences · 2026Article
- Identifying subtype-specific molecular pathways in Crohn's disease through RNA-seq and protein-protein interaction network analysis.Journal of translational autoimmunity · 2026Article
- Inflammatory bowel disease is associated with greater odds of complications following posterior lumbar fusion and further amplified for patients exposed to monoclonal antibody biologics.North American Spine Society journal · 2024Article
- Peri-Operative Optimization of Patients with Crohn's Disease.Current gastroenterology reports · 2024Review
- Perioperative Assessment and Optimization in Major Colorectal Surgery: Medication Management.Clinics in colon and rectal surgery · 2023Review
- Treatment escalation and de-escalation decisions in Crohn's disease: Delphi consensus recommendations from Japan, 2021.Journal of gastroenterology · 2023Review
- Liver Transplantation for Primary Sclerosing Cholangitis (PSC) With or Without Inflammatory Bowel Disease (IBD)-A European Society of Organ Transplantation (ESOT) Consensus Statement.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Complete Blood Count-Derived Inflammatory Markers Changes in Dogs with Chronic Inflammatory Enteropathy Treated with Adipose-Derived Mesenchymal Stem Cells.Animals : an open access journal from MDPI · 2022Article
- Aspects Towards the Anastomotic Healing in Crohn's Disease: Clinical Approach and Current Gaps in Research.Frontiers in surgery · 2022Review
- Article
- Reducing Perioperative Risks of Surgery in Crohn's Disease.Visceral medicine · 2019Review
- Article
- High-risk human papilloma virus infection and cervical neoplasm in female inflammatory bowel disease patients: a cross-sectional study.Gastroenterology report · 2019Article
- Surgery in the age of biologics.Gastroenterology report · 2019Review
- Evaluating the effectiveness of infliximab on perianal fistulizing Crohn's disease by magnetic resonance imaging.Gastroenterology report · 2019Article
- Impact of Modern Drug Therapy on Surgery: Crohn's Disease.Visceral medicine · 2018Review
- Incidence and risk factors for incisional surgical site infection in patients with Crohn's disease undergoing bowel resection.Gastroenterology report · 2018Article
- Surgical outcomes and stoma-related complications in inflammatory bowel disease in Saudi Arabia: a retrospective study.Annals of Saudi medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Crohn's disease (CD) is characterized by transmural inflammation of the gastrointestinal tract leading to inflammatory, stricturing and/or and fistulizing disease. Once a patient develops medically refractory disease, mechanical obstruction, fistulizing disease or perforation, surgery is indicated. Unfortunately, surgery is not curative in most cases, underscoring the importance of bowel preservation and adequate perioperative medical management. As many of the medications used to treat CD are immunosuppressive, the concern for postoperative infectious complications and anastomotic healing are particularly concerning; these concerns have to be balanced with preventing and treating residual or recurrent disease. We herein review the available literature and make recommendations regarding the preoperative, perioperative and postoperative administration of immunosuppressive medications in the current era of biological therapy for CD. Standardized algorithms for perioperative medical management would greatly assist future research for optimizing surgical outcomes and preventing disease recurrence in the future.
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