Evidence map›Paper›PMID 28852494›Full record

ArticleClinical kidney journal2017

Age-dependent reference intervals for estimated and measured glomerular filtration rate.

Hans Pottel, Pierre Delanaye, Laurent Weekers, Luciano Selistre, Karolien Goffin, Olivier Gheysens, Laurence Dubourg

Abstract read
In one paragraph

Article in Clinical kidney journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Prevalence of reduced eGFR in European adults using KDIGO and age-adapted eGFR thresholds.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hans PottelDepartment of Public Health and Primary Care, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium.
Pierre DelanayeNephrology-Dialysis-Transplantation, University of Liège, CHU Sart Tilman, Liège, Belgium.
Laurent WeekersNephrology-Dialysis-Transplantation, University of Liège, CHU Sart Tilman, Liège, Belgium.
Luciano SelistrePontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil.
Karolien GoffinDepartment of Nuclear Medicine, University Hospital Leuven and Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.
Olivier GheysensDepartment of Nuclear Medicine, University Hospital Leuven and Department of Imaging and Pathology, KU Leuven, Leuven, Belgium.
Laurence DubourgExploration Fonctionnelle Rénale, Groupement Hospitalier Edouard Herriot, Hospices Civils de Lyon, Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDefining mean and reference intervals for glomerular filtration rate (GFR) has been the subject of only a limited number of studies and review articles, with contradicting statements about the mean. Normal measured GFR (mGFR) values of ∼120-130 mL/min/1.73 m

methodsBased on the reference intervals for serum creatinine (SCr) and the recently published full-age spectrum (FAS) equation, we define simple age-dependent equations for the reference limits of GFR. The mGFR of 633 living potential kidney donors was used to validate the new formulae that define the reference interval.

resultsThe reference limits for estimated GFR (eGFR), calculated by entering the reference limits for SCr into the FAS equation closely correspond with published reference limits for mGFR. Of the mGFRs of potential living kidney donors, 97.2% lie between the newly defined reference limits for GFR.

conclusionSCr reference limits may serve to define age-dependent reference limits for eGFR and mGFR.

Indexed as

age-dependent reference intervalsestimated and measured glomerular filtration rate

Identifiers

PMID28852494
PMCPMC5570001

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.