Evidence map›Paper›PMID 28852487›Full record

ArticleClinical kidney journal2017

Rare genetic variants in Shiga toxin-associated haemolytic uraemic syndrome: genetic analysis prior to transplantation is essential.

Frances Dowen, Katrina Wood, Alison L Brown, Jennifer Palfrey, David Kavanagh, Vicky Brocklebank

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Shiga Toxin-ProducingKidney international reports · 2025
    Article
  2. Review
  3. Review
  4. Complement in Secondary Thrombotic Microangiopathy.Kidney international reports · 2021
    Review
  5. Review
  6. Thrombotic Microangiopathy and the Kidney.Clinical journal of the American Society of Nephrology : CJASN · 2018
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Frances DowenDepartment of Renal Medicine, Sunderland Royal Hospital, Sunderland, Tyne and Wear, UK.
Katrina WoodDepartment of Pathology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Alison L BrownRenal Services Centre, Freeman Hospital, Newcastle upon Tyne, UK.
Jennifer PalfreyDepartment of Renal Medicine, Sunderland Royal Hospital, Sunderland, Tyne and Wear, UK.
David KavanaghNational Renal Complement Therapeutics Centre, Newcastle University and Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Vicky BrocklebankNational Renal Complement Therapeutics Centre, Newcastle University and Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Newcastle upon Tyne Hospitals NHS Foundation Trust · GBSunderland Royal Hospital · GBFreeman Hospital · GBNewcastle University · GB

Funding

Medical Research Council MR/R000913/1
6 · The paper itself

Abstract

We present a case of haemolytic uraemic syndrome (HUS) in a 16-year-old female with serological evidence of acute

Indexed as

atypical haemolytic uraemic syndromecomplementeculizumabrenal transplantationSTEC-HUS

Identifiers

PMID28852487
PMCPMC5569917
OpenAlexW2744273961

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.