Evidence map›Paper›PMID 28852434›Full record

ArticleOxidative medicine and cellular longevity2017

A New Natural Antioxidant Mixture Protects against Oxidative and DNA Damage in Endothelial Cell Exposed to Low-Dose Irradiation.

T Cervelli, D Panetta, T Navarra, S Gadhiri, P Salvadori, A Galli, D Caramella, G Basta, E Picano, S Del Turco

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04154982 (Cardiac Arrhythmia Catheter Ablation Procedures Guided by x-Ray Imaging), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04154982 phase2completednot on this mapstarted 2020, after this paper: background citation

Cardiac Arrhythmia Catheter Ablation Procedures Guided by x-Ray Imaging: N-Acetylcysteine Protection Against Radiation Induced Cellular damagE (CARAPACE Study)

TypeinterventionalSponsorCentro Cardiologico MonzinoRan2020 to 2024Enrolled181ConditionsCardiac ArrhythmiaArmsAcetyl cysteine
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

T CervelliInstitute of Clinical Physiology, Council of National Research (CNR), Via Moruzzi, 1, 56124 Pisa, Italy.ORCID 0000-0002-9997-1741
D PanettaInstitute of Clinical Physiology, Council of National Research (CNR), Via Moruzzi, 1, 56124 Pisa, Italy.
T NavarraInstitute of Clinical Physiology, Council of National Research (CNR), Via Moruzzi, 1, 56124 Pisa, Italy.
S GadhiriInstitute of Clinical Physiology, Council of National Research (CNR), Via Moruzzi, 1, 56124 Pisa, Italy.
P SalvadoriInstitute of Clinical Physiology, Council of National Research (CNR), Via Moruzzi, 1, 56124 Pisa, Italy.
A GalliInstitute of Clinical Physiology, Council of National Research (CNR), Via Moruzzi, 1, 56124 Pisa, Italy.ORCID 0000-0002-9091-5639
D CaramellaRadiologia Diagnostica e Interventistica, Università di Pisa, Pisa, Italy.
G BastaInstitute of Clinical Physiology, Council of National Research (CNR), Via Moruzzi, 1, 56124 Pisa, Italy.
E PicanoInstitute of Clinical Physiology, Council of National Research (CNR), Via Moruzzi, 1, 56124 Pisa, Italy.
S Del TurcoInstitute of Clinical Physiology, Council of National Research (CNR), Via Moruzzi, 1, 56124 Pisa, Italy.ORCID 0000-0003-3722-8861
Istituto di Fisiologia Clinica · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to ionizing radiation during diagnostic procedures increases systemic oxidative stress and predisposes to higher risk of cancer and cardiovascular disease development. Many studies indicated that antioxidants protect against radiation-induced damage and have high efficacy and lack of toxicity in preventing radiation exposure damages. The purpose of this study was to investigate the

Indexed as

CytoprotectionDNA DamageAntioxidantsCell SurvivalDose-Response Relationship, RadiationHistonesHumansHuman Umbilical Vein Endothelial CellsNitric OxideOxidative StressProtective AgentsReactive Oxygen SpeciesX-RaysAntioxidantsH2AX protein, humanHistonesNitric OxideProtective AgentsReactive Oxygen Species

Identifiers

PMID28852434
PMCPMC5567450
OpenAlexW2743929006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.