Evidence map›Paper›PMID 28852433›Full record

Observational studyOxidative medicine and cellular longevity2017

Cytokines Genotype-Phenotype Correlation in Nonalcoholic Steatohepatitis.

Ioana Corina Bocsan, Mircea Vasile Milaciu, Raluca Maria Pop, Stefan Cristian Vesa, Lorena Ciumarnean, Daniela Maria Matei, Anca Dana Buzoianu

Abstract readObservational Study
In one paragraph

Observational study in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. From model to man: Understanding Tregs' dual role in MASLD.JHEP reports : innovation in hepatology · 2025
    Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Targeting macrophagic 17Acta pharmaceutica Sinica. B · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. A 3D Human Liver Model of Nonalcoholic Steatohepatitis.Journal of clinical and translational hepatology · 2020
    Article
  18. Article
  19. Review
  20. Paraoxonase-1 Serum Concentration andJournal of clinical medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ioana Corina BocsanDepartment of Pharmacology, Toxicology and Clinical Pharmacology, Iuliu Haţieganu University of Medicine and Pharmacy, Marinescu str. No.23, Cluj-Napoca, Romania.
Mircea Vasile Milaciu4th Department of Internal Medicine, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Raluca Maria PopDepartment of Pharmacology, Toxicology and Clinical Pharmacology, Iuliu Haţieganu University of Medicine and Pharmacy, Marinescu str. No.23, Cluj-Napoca, Romania.ORCID 0000-0003-1899-5977
Stefan Cristian VesaDepartment of Pharmacology, Toxicology and Clinical Pharmacology, Iuliu Haţieganu University of Medicine and Pharmacy, Marinescu str. No.23, Cluj-Napoca, Romania.
Lorena Ciumarnean3rd Department of Internal Medicine, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Daniela Maria Matei3rd Department of Internal Medicine, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Anca Dana BuzoianuDepartment of Pharmacology, Toxicology and Clinical Pharmacology, Iuliu Haţieganu University of Medicine and Pharmacy, Marinescu str. No.23, Cluj-Napoca, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NASH consists in lipid accumulation in hepatocytes that trigger oxidative stress, secretion of proinflammatory cytokines leading to steatohepatitis (NASH). The study aimed to investigate the levels of proinflammatory (TNF-

Indexed as

Genetic Association StudiesAllelesAnthropometryBiomarkersCase-Control StudiesCytokinesFemaleGenotypeHumansInflammationInterleukin-10Interleukin-6MaleMiddle AgedNon-alcoholic Fatty Liver DiseasePolymorphism, Single NucleotideBiomarkersCytokinesIL10 protein, humanInterleukin-10Interleukin-6Tumor Necrosis Factor-alpha

Identifiers

PMID28852433
PMCPMC5568617

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.