Evidence map›Paper›PMID 28852392›Full record

ArticleNeural regeneration research2017

Neural differentiation of human Wharton's jelly-derived mesenchymal stem cells improves the recovery of neurological function after transplantation in ischemic stroke rats.

Lei Zhang, Lin-Mei Wang, Wei-Wei Chen, Zhi Ma, Xiao Han, Cheng-Ming Liu, Xiang Cheng, Wei Shi, Jing-Jing Guo, Jian-Bing Qin and 3 more

Open access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Lei ZhangDepartment of Anatomy, Nantong University, Nantong, Jiangsu Province, China.
Lin-Mei WangDepartment of Anatomy, Nantong University, Nantong, Jiangsu Province, China.
Wei-Wei ChenDepartment of Radiation Oncology, Third People's Hospital of Yancheng, Yancheng, Jiangsu Province, China.
Zhi MaDepartment of Anatomy, Nantong University, Nantong, Jiangsu Province, China.
Xiao HanDepartment of Anatomy, Nantong University, Nantong, Jiangsu Province, China.
Cheng-Ming LiuDepartment of Anatomy, Nantong University, Nantong, Jiangsu Province, China.
Xiang ChengDepartment of Anatomy, Nantong University, Nantong, Jiangsu Province, China.
Wei ShiDepartment of Neurosurgery, the Affiliated Hosptial of Nantong University, Nantong, Jiangsu Province, China.
Jing-Jing GuoDepartment of Anatomy, Nantong University, Nantong, Jiangsu Province, China.
Jian-Bing QinDepartment of Anatomy, Nantong University, Nantong, Jiangsu Province, China.
Xiao-Qing YangDepartment of Obstetrics and Gynecology, the Affiliated Hosptial of Nantong University, Nantong, Jiangsu Province, China.
Guo-Hua JinDepartment of Anatomy, Nantong University, Nantong, Jiangsu Province, China.
Xin-Hua ZhangDepartment of Anatomy, Nantong University, Nantong, Jiangsu Province, China.ORCID 0000-0002-5702-6733
Nantong University · CNAffiliated Hospital of Nantong University · CNYancheng Third People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human Wharton's jelly-derived mesenchymal stem cells (hWJ-MSCs) have excellent proliferative ability, differentiation ability, low immunogenicity, and can be easily obtained. However, there are few studies on their application in the treatment of ischemic stroke, therefore their therapeutic effect requires further verification. In this study, hWJ-MSCs were transplanted into an ischemic stroke rat model

Indexed as

cell transplantationhuman Wharton's jelly-derived mesenchymal stem cellsischemic strokemiddle cerebral artery occlusionnerve regenerationneural differentiationneural regenerationneurological function

Identifiers

PMID28852392
PMCPMC5558489
OpenAlexW2739142777

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.