Evidence map›Paper›PMID 28852319›Full record

Observational studyWorld journal of gastroenterology2017

Combination of acoustic radiation force impulse imaging, serological indexes and contrast-enhanced ultrasound for diagnosis of liver lesions.

Xiao-Lan Sun, Hui Yao, Qiong Men, Ke-Zhu Hou, Zhen Chen, Chang-Qing Xu, Li-Wei Liang

Open access · hybridAbstract readComparative StudyObservational StudyValidation Study
In one paragraph

Observational study in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Prognostic Value of Quantitative Perfusion Parameters by Enhanced Ultrasound in Endometrial Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xiao-Lan SunXiao-Lan Sun, Department of Ultrasound, Shanghai Yangpu District East Hospital, Shanghai 200433, China.
Hui YaoXiao-Lan Sun, Department of Ultrasound, Shanghai Yangpu District East Hospital, Shanghai 200433, China.
Qiong MenXiao-Lan Sun, Department of Ultrasound, Shanghai Yangpu District East Hospital, Shanghai 200433, China.
Ke-Zhu HouXiao-Lan Sun, Department of Ultrasound, Shanghai Yangpu District East Hospital, Shanghai 200433, China.
Zhen ChenXiao-Lan Sun, Department of Ultrasound, Shanghai Yangpu District East Hospital, Shanghai 200433, China.
Chang-Qing XuXiao-Lan Sun, Department of Ultrasound, Shanghai Yangpu District East Hospital, Shanghai 200433, China.
Li-Wei LiangXiao-Lan Sun, Department of Ultrasound, Shanghai Yangpu District East Hospital, Shanghai 200433, China.
YangPu Geriatric Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the value of combined acoustic radiation force impulse (ARFI) imaging, serological indexes and contrast-enhanced ultrasound (CEUS) in distinguishing between benign and malignant liver lesions.

methodsPatients with liver lesions treated at our hospital were included in this study. The lesions were divided into either a malignant tumor group or a benign tumor group according to pathological or radiological findings. ARFI quantitative detection, serological testing and CEUS quantitative detection were performed and compared. A comparative analysis of the measured indexes was performed between these groups. Receiver operating characteristic (ROC) curves were constructed to compare the diagnostic accuracy of ARFI imaging, serological indexes and CEUS, alone or in different combinations, in identifying benign and malignant liver lesions.

resultsA total of 112 liver lesions in 43 patients were included, of which 78 were malignant and 34 were benign. Shear wave velocity (SWV) value, serum alpha-fetoprotein (AFP) content and enhancement rate were significantly higher in the malignant tumor group than in the benign tumor group (2.39 ± 1.20 m/s

conclusionThe combination of SWV, AFP and enhancement rate had better diagnostic performance in distinguishing between benign and malignant liver lesions than the use of any single parameter or the combination of any two of parameters. It is expected that this would provide a tool for the differential diagnosis of benign and malignant liver lesions.

Indexed as

alpha-FetoproteinsBiopsy, NeedleCarcinoma, HepatocellularContrast MediaDiagnosis, DifferentialElasticity Imaging TechniquesFemaleHumansLiverLiver NeoplasmsMaleRadiographyROC CurveSensitivity and SpecificityUltrasonographyalpha-FetoproteinsContrast MediaBenignCombined diagnosisDifferentiationLiver lesionsMalignant

Identifiers

PMID28852319
PMCPMC5558123
OpenAlexW2745897049

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.