ArticleIndian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
The Bone Pain Crisis of Sickle Cell Disease and Malaria: Observations from Gujarat, India.
Article in Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 7 citations in OpenAlex.
- Diagnostic relevance of osteocalcin and bone alkaline phosphatase as markers of bone turnover in Sickle Cell Anaemia: A Zaria study.African health sciences · 2026Article
- The Relationship Between Malaria and Pain: A Mini-Review.The American journal of tropical medicine and hygiene · 2025Review
- Sickle Cell Disease: Thoughts for India From the Jamaican Cohort Study.Frontiers in medicine · 2021Review
- Sickle cell disease in Sri Lanka: clinical and molecular basis and the unanswered questions about disease severity.Orphanet journal of rare diseases · 2020Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
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Abstract
backgroundSickle cell disease is a common problem across central India, but its clinical features may differ from that in African populations. There is a need to define the features of sickle cell disease in India, and the current study addresses some features of the bone pain crisis.
objectivesThe objective of the study was to describe the epidemiology of the bone pain crisis of sickle cell disease in Gujarat and explore the relationship with infection by MATERIALS AND
methodsThis was a prospective review of all admissions in patients with sickle cell disease to a private pediatric institution in Bardoli, Gujarat, in the year 2015. Hemoglobin electrophoresis of all patients was consistent with homozygous sickle cell disease, but family studies indicated that at least seven cases had the severe sickle cell-beta + thalassemia presumed to be the common IVS1-5G>C mutation. Clinical, hematological, and parasitological features were recorded.
resultsThere were 914 admissions among 654 patients who had between one and seven admissions. The bone pain crisis accounted for 763 (83%) of admissions and increased between July and October coinciding with the monsoon period. Blood smears were examined for malarial parasites in 811 admissions and were positive for
conclusionsThere was a high prevalence of
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