Evidence map›Paper›PMID 28852058›Full record

ArticleScientific reports2017

Key glycolytic branch influences mesocarp oil content in oil palm.

Nurliyana Ruzlan, Yoke Sum Jaime Low, Wilonita Win, Noor Azizah Musa, Ai-Ling Ong, Fook-Tim Chew, David Appleton, Hirzun Mohd Yusof, Harikrishna Kulaveerasingam

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. The effect on shikimate production by deletingFrontiers in bioengineering and biotechnology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Nurliyana RuzlanSime Darby Renewables, Sime Darby Plantation Sdn Bhd, Selangor, Malaysia. nurliyana.ruzlan@simedarby.com.
Yoke Sum Jaime LowBiotechnology & Breeding Department, Sime Darby Plantation R&D Centre, Selangor, Malaysia.
Wilonita WinBiotechnology & Breeding Department, Sime Darby Plantation R&D Centre, Selangor, Malaysia.
Noor Azizah MusaBiotechnology & Breeding Department, Sime Darby Plantation R&D Centre, Selangor, Malaysia.
Ai-Ling OngBiotechnology & Breeding Department, Sime Darby Plantation R&D Centre, Selangor, Malaysia.ORCID 0000-0002-8383-7273
Fook-Tim ChewDepartment of Biological Sciences, National University of Singapore, Singapore, Singapore.ORCID 0000-0003-1337-5146
David AppletonBiotechnology & Breeding Department, Sime Darby Plantation R&D Centre, Selangor, Malaysia.ORCID 0000-0001-8570-1428
Hirzun Mohd YusofSime Darby Renewables, Sime Darby Plantation Sdn Bhd, Selangor, Malaysia.
Harikrishna KulaveerasingamBiotechnology & Breeding Department, Sime Darby Plantation R&D Centre, Selangor, Malaysia.
National University of Singapore · SGSimulation Technologies (United States) · USSubang Jaya Medical Centre · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fructose-1,6-bisphosphate aldolase catalyzed glycolysis branch that forms dihydroxyacetone phosphate and glyceraldehyde-3-phosphate was identified as a key driver of increased oil synthesis in oil palm and was validated in Saccharomyces cerevisiae. Reduction in triose phosphate isomerase (TPI) activity in a yeast knockdown mutant resulted in 19% increase in lipid content, while yeast strains overexpressing oil palm fructose-1,6-bisphosphate aldolase (EgFBA) and glycerol-3-phosphate dehydrogenase (EgG3PDH) showed increased lipid content by 16% and 21%, respectively. Genetic association analysis on oil palm SNPs of EgTPI SD_SNP_000035801 and EgGAPDH SD_SNP_000041011 showed that palms harboring homozygous GG in EgTPI and heterozygous AG in EgGAPDH exhibited higher mesocarp oil content based on dry weight. In addition, AG genotype of the SNP of EgG3PDH SD_SNP_000008411 was associated with higher mean mesocarp oil content, whereas GG genotype of the EgFBA SNP SD_SNP_000007765 was favourable. Additive effects were observed with a combination of favourable alleles in TPI and FBA in Nigerian x AVROS population (family F7) with highest allele frequency GG.GG being associated with a mean increase of 3.77% (p value = 2.3E

Indexed as

GlycolysisArecaceaeFructose-Bisphosphate AldolaseGenetic Association StudiesGenotypeGlyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)Glycerolphosphate DehydrogenasePlant OilsPlant ProteinsPolymorphism, Single NucleotideRecombinant ProteinsSaccharomyces cerevisiaeTriose-Phosphate IsomeraseFructose-Bisphosphate AldolaseGlyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)Glycerolphosphate DehydrogenasePlant OilsPlant ProteinsRecombinant ProteinsTriose-Phosphate Isomerase

Identifiers

PMID28852058
PMCPMC5575415
OpenAlexW2745626168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.