Evidence map›Paper›PMID 28852011›Full record

ArticleScientific reports2017

Genome-Wide Linkage-Disequilibrium Mapping to the Candidate Gene Level in Melon (Cucumis melo).

Amit Gur, Galil Tzuri, Ayala Meir, Uzi Sa'ar, Vitaly Portnoy, Nurit Katzir, Arthur A Schaffer, Li Li, Joseph Burger, Yaakov Tadmor

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Meta genetic analysis of melon sweetness.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Pooled it
  2. Introgression line libraries in melon (Molecular breeding : new strategies in plant improvement · 2026
    Review
  3. Article
  4. Article
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  6. Article
  7. Horticulture research · 2025
    Article
  8. Article
  9. A Rare Frameshift Mutation of inPlants (Basel, Switzerland) · 2025
    Article
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  11. Article
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amit GurPlant Science Institute, Agricultural Research Organization, Newe Ya'ar Research Center, P.O. Box 1021, Ramat Yishay, 3009500, Israel. amitgur@volcani.agri.gov.il.
Galil TzuriPlant Science Institute, Agricultural Research Organization, Newe Ya'ar Research Center, P.O. Box 1021, Ramat Yishay, 3009500, Israel.
Ayala MeirPlant Science Institute, Agricultural Research Organization, Newe Ya'ar Research Center, P.O. Box 1021, Ramat Yishay, 3009500, Israel.
Uzi Sa'arPlant Science Institute, Agricultural Research Organization, Newe Ya'ar Research Center, P.O. Box 1021, Ramat Yishay, 3009500, Israel.
Vitaly PortnoyPlant Science Institute, Agricultural Research Organization, Newe Ya'ar Research Center, P.O. Box 1021, Ramat Yishay, 3009500, Israel.ORCID 0000-0003-1130-6788
Nurit KatzirPlant Science Institute, Agricultural Research Organization, Newe Ya'ar Research Center, P.O. Box 1021, Ramat Yishay, 3009500, Israel.
Arthur A SchafferPlant Science Institute, Agricultural Research Organization, The Volcani Center, P.O. Box 15159, Rishon LeZiyyon, 7505101, Israel.
Li LiRobert W Holley Center for Agriculture and Health, USDA-ARS, Plant Breeding and Genetics Section, School of Integrative Plant Science, Cornell University, Ithaca, New York, 14853, USA.
Joseph BurgerPlant Science Institute, Agricultural Research Organization, Newe Ya'ar Research Center, P.O. Box 1021, Ramat Yishay, 3009500, Israel.
Yaakov TadmorPlant Science Institute, Agricultural Research Organization, Newe Ya'ar Research Center, P.O. Box 1021, Ramat Yishay, 3009500, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cucumis melo is highly diverse for fruit traits providing wide breeding and genetic research opportunities, including genome-wide association (GWA) analysis. We used a collection of 177 accessions representing the two C. melo subspecies and 11 horticultural groups for detailed characterization of fruit traits variation and evaluation of the potential of GWA for trait mapping in melon. Through genotyping-by-sequencing, 23,931 informative SNPs were selected for genome-wide analyses. We found that linkage-disequilibrium decays at ~100 Kb in this collection and that population structure effect on association results varies between traits. We mapped several monogenic traits to narrow intervals overlapping with known causative genes, demonstrating the potential of diverse collections and GWA for mapping Mendelian traits to a candidate-gene level in melon. We further report on mapping of fruit shape quantitative trait loci (QTLs) and comparison with multiple previous QTL studies. Expansion of sample size and a more balanced representation of taxonomic groups might improve efficiency for simple traits dissection. But, as in other plant species, integrated linkage-association multi-allelic approaches are likely to produce better combination of statistical power, diversity capture and mapping resolution in melon. Our data can be utilized for selection of the most appropriate accessions for such approaches.

Indexed as

Chromosome MappingGenes, PlantGenome, PlantGenome-Wide Association StudyLinkage DisequilibriumCucurbitaceaeFruitGenetic LinkageGenetic VariationPhenotypeQuantitative Trait, HeritableQuantitative Trait Loci

Identifiers

PMID28852011
PMCPMC5575340

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.