Evidence map›Paper›PMID 28851954›Full record

ArticleScientific reports2017

Interleukin-6, tumor necrosis factor-alpha and receptor activator of nuclear factor kappa ligand are elevated in hypertrophic gastric mucosa of pachydermoperiostosis.

Hui Huang, Yongjun Wang, Yong Cao, Boda Wu, Yonggui Li, Liangliang Fan, Zhiping Tan, Yi Jiang, Jianguang Tang, Jianzhong Hu and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Endocrine Alterations in Patients With Pachydermoperiostosis.The Journal of clinical endocrinology and metabolism · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Hui HuangDepartment of Medical Genetics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Yongjun WangDepartment of Gastroenterology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Yong CaoDepartment of Spine Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China.
Boda WuDepartment of Medical Genetics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Yonggui LiDepartment of Medical Genetics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Liangliang FanThe Thoracic Surgery Research Room, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Zhiping TanThe Thoracic Surgery Research Room, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Yi JiangDepartment of Pathology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Jianguang TangDepartment of Neurology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
Jianzhong HuDepartment of Spine Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, 410008, China. jianzhonghu@hotmail.com.
Xiaoliu ShiDepartment of Medical Genetics, The Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China. shixl6@csu.edu.cn.
Central South University · CNSecond Xiangya Hospital of Central South University · CNXiangya Hospital Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pachydermoperiostosis (PDP) is a rare inherited multisystem disease characterized with digital clubbing, pachydermia and periostosis. Variants in either HPGD or SLCO2A1 that interrupt the prostaglandin E2 (PGE

Indexed as

BiomarkersBiopsyCelecoxibDNA Mutational AnalysisGastric MucosaHumansHypertrophyImmunohistochemistryInterleukin-6Intramolecular OxidoreductasesMaleMutationOrganic Anion TransportersOsteoarthropathy, Primary HypertrophicPedigreePhenotypeBiomarkersCelecoxibInterleukin-6Intramolecular OxidoreductasesOrganic Anion TransportersRANK LigandSLCO2A1 protein, humanTumor Necrosis Factor-alpha

Identifiers

PMID28851954
PMCPMC5574921
OpenAlexW2747302942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.