ArticleNature communications2017
Multifunctional quantum dot DNA hydrogels.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed.
- Recent Advances in Nanocomposite Hydrogel Sensors for Healthcare Applications: Fabrication Techniques, Multifunctionality and Challenges.Nanomaterials (Basel, Switzerland) · 2026Review
- Bioengineering DNA-based hydrogels for regenerative medicine: A review of programmable design, chemical synthesis and therapeutic potential.Materials today. Bio · 2026Review
- A multiplexed assay by self-assembled dual-target responsive DNA hydrogels for efficacy evaluation of immunotherapy.Nature communications · 2025Article
- Review
- Porous covalent architecture-involved luminescent smart hydrogel with target-responsive framework for signal-amplified inspection of aflatoxin B1.Mikrochimica acta · 2025Article
- Fluorescent probes in autoimmune disease research: current status and future prospects.Journal of translational medicine · 2025Review
- Polyelectrolyte-Carbon Dot Complex Coacervation.ACS macro letters · 2025Article
- Facile control of giant green-emission in multifunctional ZnO quantum dots produced in a single-step process: femtosecond pulse ablation.Nanoscale advances · 2025Article
- Magnetic augmentation through multi-gradient coupling enables direct and programmable profiling of circulating biomarkers.Nature communications · 2024Article
- Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis.Acta pharmaceutica Sinica. B · 2023Review
- Emerging Progress of RNA-Based Antitumor Therapeutics.International journal of biological sciences · 2023Review
- Construction of multifunctional carboxymethyl cellulose nanohydrogel carriers based on near-infrared DNA-templated quantum dots for tumor theranostics.RSC advances · 2022Article
- Application of "Click" Chemistry in Biomedical Hydrogels.ACS omega · 2022Review
- Light responsive nucleic acid for biomedical application.Exploration (Beijing, China) · 2022Review
- Quantum Dots for Cancer-Related miRNA Monitoring.ACS sensors · 2022Review
- Extracellular Vesicles Derived from SIPA1Biology · 2022Article
- Flexible photoelectrochemical sensor for highly sensitive chloramphenicol detection based on M-TiOAnalytical and bioanalytical chemistry · 2022Article
- Stimuli-responsive DNA-based hydrogels for biosensing applications.Journal of nanobiotechnology · 2022Review
- Smart Nucleic Acid Hydrogels with High Stimuli-Responsiveness in Biomedical Fields.International journal of molecular sciences · 2022Review
- SiRNA-templated 3D framework nucleic acids for chemotactic recognition, and programmable and visualized precise delivery for synergistic cancer therapy.Chemical science · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biotemplated nanomaterials offer versatile functionality for multimodal imaging, biosensing, and drug delivery. There remains an unmet need for traceable and biocompatible nanomaterials that can be synthesized in a precisely controllable manner. Here, we report self-assembled quantum dot DNA hydrogels that exhibit both size and spectral tunability. We successfully incorporate DNA-templated quantum dots with high quantum yield, long-term photostability, and low cytotoxicity into a hydrogel network in a single step. By leveraging DNA-guided interactions, we introduce multifunctionality for a variety of applications, including enzyme-responsive drug delivery and cell-specific targeting. We report that quantum dot DNA hydrogels can be used for delivery of doxorubicin, an anticancer drug, to increase potency 9-fold against cancer cells. This approach also demonstrated high biocompatibility, trackability, and in vivo therapeutic efficacy in mice bearing xenografted breast cancer tumors. This work paves the way for the development of new tunable biotemplated nanomaterials with multiple synergistic functionalities for biomedical applications.The development of nanomaterials for imaging and drug delivery has been of great interest to the field. Here, the authors synthesized multifunctional enzyme-responsive hydrogels with self-assembling quantum dots for nucleic acid and drug delivery as well as having imaging capability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.