Evidence map›Paper›PMID 28851866›Full record

ArticleNature communications2017

Agricultural pesticide use and adverse birth outcomes in the San Joaquin Valley of California.

Ashley E Larsen, Steven D Gaines, Olivier Deschênes

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
19.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 162 citations in OpenAlex.

  1. Article
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  7. One landscape does not fit all: Diverse arthropod responses to land use.Ecological applications : a publication of the Ecological Society of America · 2025
    Article
  8. Glyphosate exposure and GM seed rollout unequally reduced perinatal health.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  11. Review
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ashley E LarsenBren School of Environmental Science & Management, University of California, Santa Barbara, 93106-5131, USA. Larsen@bren.ucsb.edu.
Steven D GainesBren School of Environmental Science & Management, University of California, Santa Barbara, 93106-5131, USA.
Olivier DeschênesEconomics Department, University of California, Santa Barbara, 93106-9210, USA.
University of California, Santa Barbara · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virtually all agricultural communities worldwide are exposed to agricultural pesticides. Yet, the health consequences of such exposure are poorly understood, and the scientific literature remains ambiguous. Using individual birth and demographic characteristics for over 500 000 birth observations between 1997-2011 in the agriculturally dominated San Joaquin Valley, California, we statistically investigate if residential agricultural pesticide exposure during gestation, by trimester, and by toxicity influences birth weight, gestational length, or birth abnormalities. Overall, our analysis indicates that agricultural pesticide exposure increases adverse birth outcomes by 5-9%, but only among the population exposed to very high quantities of pesticides (e.g., top 5th percentile, i.e., ~4200 kg applied over gestation). Thus, policies and interventions targeting the extreme right tail of the pesticide distribution near human habitation could largely eliminate the adverse birth outcomes associated with agricultural pesticide exposure documented in this study.The health consequences of exposure to pesticides are uncertain and subject to much debate. Here, the effect of exposure during pregnancy is investigated in an agriculturally dominated residential area, showing that an increase in adverse birth outcomes is observed with very high levels of pesticide exposure.

Indexed as

AgricultureBirth WeightCaliforniaDose-Response Relationship, DrugEnvironmental ExposureFemaleFetal DevelopmentFetal WeightHumansInfant, NewbornMaternal ExposurePesticidesPregnancyPrenatal Exposure Delayed EffectsPesticides

Identifiers

PMID28851866
PMCPMC5575123
OpenAlexW2743540986

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.