ArticleMedical science monitor : international medical journal of experimental and clinical research2017
Effect of Probiotic Lactobacilli on the Growth of Streptococcus Mutans and Multispecies Biofilms Isolated from Children with Active Caries.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Effect of probiotic interventions on oral health in children: a systematic review.Frontiers in dental medicine · 2026Pooled it
- Investigation of the anti-microbial and anti-inflammatory properties of Weizmannia coagulans MBBCM9™ and formulation of a probiotic oral health product.World journal of microbiology & biotechnology · 2026Article
- Anti-Cariogenic Potential of Lyophilized Cell-Free Supernatant of ProbioticJournal of microbiology and biotechnology · 2026Article
- The role of probiotics in modulating cariogenic bacteria and oral health outcomes: A systematic review and risk of bias assessment.The Saudi dental journal · 2025Review
- Preventive effects of probiotics on dental caries in vitro and in vivo.BMC oral health · 2024Article
- The role ofJournal of oral microbiology · 2024Review
- Antagonistic activity of Lactobacillus spp. and Bifidobacterium spp. against cariogenic Streptococcus mutans in vitro and viability when added to chewing gum during storage.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023Article
- Comparison of antibacterial effect of plantaricin 149 suspension and traditional root canal irrigation solutions in root canal infections in vitro.BMC oral health · 2022Article
- Inhibition of Streptococcus mutans Biofilm Formation by the Joint Action of Oxyresveratrol and Lactobacillus casei.Applied and environmental microbiology · 2022Article
- Antibacterial and Antibiofilm Effect of Cell-Free Supernatant ofJournal of microbiology and biotechnology · 2022Article
- Prebiotics-A Primeval Measure to Combat Dental Caries: A Short-term Clinical Study.International journal of clinical pediatric dentistry · 2022Article
- Identification of a new probiotic strain,Frontiers in microbiology · 2022Article
- Using Lactobacilli to FightAntibiotics (Basel, Switzerland) · 2021Article
- Evaluation of the antibacterial effects and mechanism of Plantaricin 149 from Lactobacillus plantarum NRIC 149 on the peri-implantitis pathogens.Scientific reports · 2021Article
- Effect ofAntibiotics (Basel, Switzerland) · 2021Article
- [Association of sepM gene mutation with mutacin Ⅳ production byNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021Article
- Quantification and gene expression ofThe Saudi dental journal · 2021Article
- Effects of Probiotic Culture Supernatant on Cariogenic Biofilm Formation and RANKL-Induced Osteoclastogenesis in RAW 264.7 Macrophages.Molecules (Basel, Switzerland) · 2021Article
- Effects of probiotic and fluoride mouthrinses onDental research journal · 2021Article
- DMF Index among Amelogenesis Imperfecta Patients: Systematic Review of the Literature.International journal of dentistry · 2021Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND The purpose of this investigation was to evaluate the effect of probiotic lactobacilli on Streptococcus mutans (MS) and multispecies biofilms isolated from children with severe caries. MATERIAL AND METHODS Twenty children with active caries (DMFS ≥6) were selected as the experimental group and Streptococcus mutans (MS) were isolated from their saliva. After identification the MS strains were mixed with lactobacilli at 37°C, following which viable MS colonies were counted. At the same time dental plaques from the children were mixed with lactobacilli in vitro to form biofilms, and the population of nine common strains in the biofilms was enumerated after 24 hours of growth. RESULTS Lactobacillus casei Shirota, L. casei LC01, L. plantarum ST-III and L. paracasei LPC37 all had strong inhibitory effects on the majority the MS isolated from children with active caries, with the inhibition rate reaching approximately 70-90% (p<0.05). L. casei Shirota, L. casei LC01, L. plantarum ST-III, L. paracasei LPC37 also significantly reduced the numbers of MS, Streptococcus spp., S. sanguinis and total bacteria in mixed biofilms compared with the control group (p<0.05). CONCLUSIONS The four strains of lactobacilli were able to inhibit the growth of Streptococcus mutans and had effects on the composition of bacterial biofilms in vitro. Ingestion of probiotics may be a promising method of caries prevention.
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