Evidence map›Paper›PMID 28851853›Full record

ArticlemBio2017

Translational Repression of the RpoS Antiadapter IraD by CsrA Is Mediated via Translational Coupling to a Short Upstream Open Reading Frame.

Hongmarn Park, Louise C McGibbon, Anastasia H Potts, Helen Yakhnin, Tony Romeo, Paul Babitzke

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Multitier regulation of theJournal of bacteriology · 2024
    Article
  6. RpoS and the bacterial general stress response.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  7. Article
  8. CsrA-Mediated Translational Activation of theJournal of bacteriology · 2023
    Article
  9. CsrA Shows Selective Regulation of sRNA-mRNA Networks.bioRxiv : the preprint server for biology · 2023
    Article
  10. Article
  11. CsrA selectively modulates sRNA-mRNA regulator outcomes.Frontiers in molecular biosciences · 2023
    Article
  12. Article
  13. Combined Transcriptomic and Proteomic Profiling ofInternational journal of molecular sciences · 2022
    Article
  14. Article
  15. EcoSal Plus · 2020
    Review
  16. Review
  17. Review
  18. Genomic Survey ofFrontiers in microbiology · 2020
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hongmarn ParkDepartment of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA.
Louise C McGibbonDepartment of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA.
Anastasia H PottsDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, USA.
Helen YakhninDepartment of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA.
Tony RomeoDepartment of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, Florida, USA.
Paul BabitzkeDepartment of Biochemistry and Molecular Biology, Center for RNA Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, USA pxb28@psu.edu.ORCID 0000-0003-2481-1062
Pennsylvania State University · USUniversity of Florida · US

Funding

Mechanism of CsrA-mediated global regulationR01GM059969 · NIGMS · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI BABITZKE, PAUL L, ROMEO, TONY · 1999 to 2021
$7.6M
NIGMS NIH HHS R01 GM059969
6 · The paper itself

Abstract

CsrA is a global regulatory RNA binding protein that has important roles in regulating carbon metabolism, motility, biofilm formation, and numerous other cellular processes. IraD functions as an antiadapter protein that inhibits RssB-mediated degradation of RpoS, the general stress response and stationary-phase sigma factor of

Indexed as

Gene Expression Regulation, BacterialOpen Reading FramesBacterial ProteinsEscherichia coliEscherichia coli ProteinsProtein BiosynthesisRepressor ProteinsRNA, BacterialRNA-Binding ProteinsRNA, MessengerSigma FactorTranscription FactorsBacterial ProteinsCsrA protein, E coliEscherichia coli ProteinsIraD protein, E coliRepressor ProteinsRNA, BacterialRNA-Binding ProteinsRNA, MessengerSigma Factorsigma factor KatF protein, BacteriaTranscription FactorsCsrAIraDRpoStranslational controltranslational coupling

Identifiers

PMID28851853
PMCPMC5574718
OpenAlexW2753358590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.