Evidence map›Paper›PMID 28851846›Full record

ArticlemBio2017

Cardiolipin Synthesis and Outer Membrane Localization Are Required for

Rachael M Rossi, Lauren Yum, Hervé Agaisse, Shelley M Payne

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Fenofibrate suppressesFrontiers in cellular and infection microbiology · 2025
    Article
  7. Review
  8. Strain ofPlants (Basel, Switzerland) · 2024
    Article
  9. Article
  10. Enhancing the Efficacy of Chloramphenicol Therapy forAntibiotics (Basel, Switzerland) · 2024
    Article
  11. Article
  12. Article
  13. Review
  14. Shigella Outer Membrane Vesicles as Promising Targets for Vaccination.International journal of molecular sciences · 2022
    Review
  15. Review
  16. Border Control: Regulating LPS Biogenesis.Trends in microbiology · 2021
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rachael M RossiDepartment of Molecular Biosciences and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas, USA.
Lauren YumDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Hervé AgaisseDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Shelley M PayneDepartment of Molecular Biosciences and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas, USA payne@utexas.edu.
The University of Texas at Austin · USUniversity of Virginia · US

Funding

ROLE OF CARBON METABOLISM AND VIRULENCE OF SHIGELLA FLEXNERIR37AI016935 · NIAID · UNIVERSITY OF TEXAS AUSTIN · PI Shelley M. Payne · 2003 to 2026
$6.0M
Mechanisms of intracellular pathogen disseminationR01AI073904 · NIAID · YALE UNIVERSITY · PI AGAISSE, HERVE F · 2007 to 2022
$5.5M
Role of carbon metabolism in virulence of Shigella flexneriR01AI016935 · NIAID · UNIVERSITY OF TEXAS AUSTIN · PI PAYNE, SHELLEY M. · 1985 to 2017
$2.6M
NIAID NIH HHS R01 AI016935NIAID NIH HHS R01 AI073904NIAID NIH HHS R37 AI016935
6 · The paper itself

Abstract

Cardiolipin, an anionic phospholipid that resides at the poles of the inner and outer membranes, is synthesized primarily by the putative cardiolipin synthase ClsA in

Indexed as

ActinsBacterial Outer Membrane ProteinsBacterial ProteinsCardiolipinsCytoplasmDNA-Binding ProteinsHumansMembrane ProteinsMutationShigella flexneriTransferases (Other Substituted Phosphate Groups)VirulenceActinsBacterial Outer Membrane ProteinsBacterial ProteinsCardiolipinscardiolipin synthetaseDNA-Binding ProteinsMembrane ProteinsTransferases (Other Substituted Phosphate Groups)cardiolipincell-cell spreadIcsAouter membraneShigella flexneri

Identifiers

PMID28851846
PMCPMC5574711
OpenAlexW2750988024

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.