Evidence map›Paper›PMID 28851823›Full record

ArticleScience signaling2017

Activation of master virulence regulator PhoP in acidic pH requires the

Jeongjoon Choi, Eduardo A Groisman

Abstract read
In one paragraph

Article in Science signaling, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Large Roles of Small Proteins.Annual review of microbiology · 2024
    Review
  6. Critical role ofApplied and environmental microbiology · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Advancing evolution: Bacteria break down gene silencer to express horizontally acquired genes.BioEssays : news and reviews in molecular, cellular and developmental biology · 2023
    Article
  13. Nitrate Utilization Promotes Systemic Infection ofInternational journal of molecular sciences · 2022
    Article
  14. Article
  15. TheFrontiers in microbiology · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. How the PhoP/PhoQ System Controls Virulence and MgMicrobiology and molecular biology reviews : MMBR · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jeongjoon ChoiDepartment of Microbial Pathogenesis, Yale School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA.ORCID http://orcid.org/0000-0002-4137-6923
Eduardo A GroismanDepartment of Microbial Pathogenesis, Yale School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA. eduardo.groisman@yale.edu.ORCID http://orcid.org/0000-0001-6860-7691
Yale University · US

Funding

Expanding the SensingAbilities of Virulence Regulatory SystemsR01AI120558 · NIAID · YALE UNIVERSITY · PI GROISMAN, EDUARDO · 2016 to 2019
$2.2M
NIAID NIH HHS R01 AI120558
6 · The paper itself

Abstract

Acidic conditions, such as those inside phagosomes, stimulate the intracellular pathogen

Indexed as

AnimalsAntimicrobial Cationic PeptidesBacterial ProteinsDisease Models, AnimalFemaleGene Expression Regulation, BacterialHydrogen-Ion ConcentrationMagnesiumMembrane ProteinsMiceMice, Inbred BALB CPeptidesPhosphorylationSalmonella InfectionsSalmonella typhimuriumSignal TransductionAntimicrobial Cationic PeptidesBacterial ProteinsC18G peptideMagnesiumMembrane ProteinsPeptidesPhoP protein, BacteriaPhoQ protein, BacteriaUgtL protein, Salmonella typhimurium

Identifiers

PMID28851823
PMCPMC5966036
OpenAlexW2753174033

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.