Evidence map›Paper›PMID 28851736›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2018

Short-term changes in diet composition do not affect in vivo hepatic protein synthesis in rats.

Andrea Lee Estrada, William Max Hudson, Paul Y Kim, Claire Marie Stewart, Frederick F Peelor, Yuren Wei, Dong Wang, Karyn L Hamilton, Benjamin F Miller, Michael J Pagliassotti

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Differential effects of vitamin C or protandim on skeletal muscle adaptation to exercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Andrea Lee EstradaDepartment of Food Science and Human Nutrition, Colorado State University , Fort Collins, Colorado.
William Max HudsonDepartment of Food Science and Human Nutrition, Colorado State University , Fort Collins, Colorado.
Paul Y KimDepartment of Biology, Grambling State University, Grambling, Louisiana.
Claire Marie StewartDepartment of Food Science and Human Nutrition, Colorado State University , Fort Collins, Colorado.
Frederick F PeelorDepartment of Health and Exercise Science, Colorado State University , Fort Collins, Colorado.
Yuren WeiDepartment of Food Science and Human Nutrition, Colorado State University , Fort Collins, Colorado.
Dong WangDepartment of Food Science and Human Nutrition, Colorado State University , Fort Collins, Colorado.
Karyn L HamiltonDepartment of Health and Exercise Science, Colorado State University , Fort Collins, Colorado.
Benjamin F MillerDepartment of Health and Exercise Science, Colorado State University , Fort Collins, Colorado.
Michael J PagliassottiDepartment of Food Science and Human Nutrition, Colorado State University , Fort Collins, Colorado.
Colorado State University · USGrambling State University · US

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
Obesity and Hepatic SteatosisR01DK072017 · NIDDK · COLORADO STATE UNIVERSITY-FORT COLLINS · PI PAGLIASSOTTI, MICHAEL J · 2005 to 2014
$2.2M
Translational mechanisms of mitochondrial protein synthesisR01AG042569 · NIA · COLORADO STATE UNIVERSITY · PI HAMILTON, KARYN L, MILLER, BENJAMIN FRANCIS · 2013 to 2017
$1.5M
Obesity and Hepatic SteatosisR56DK072017 · NIDDK · COLORADO STATE UNIVERSITY · PI PAGLIASSOTTI, MICHAEL J · 2010 to 2010
$249k
NIA NIH HHS R01 AG042569NIDDK NIH HHS P30 DK048520NIDDK NIH HHS R01 DK072017NIDDK NIH HHS R56 DK072017
6 · The paper itself

Abstract

Protein synthesis is critical to protein homeostasis (proteostasis), and modifications in protein synthesis influence lifespan and the development of comorbidities associated with obesity. In the present study, we examined the acute response of liver protein synthesis to either high-fat or high-sucrose diets in order to elucidate nutrient-mediated regulation of hepatic protein synthesis in the absence of body fat accumulation. Total and endoplasmic reticulum-associated protein syntheses were assessed by use of the stable isotope, deuterium oxide (

Indexed as

DietProtein BiosynthesisAnimalsBody CompositionDietary CarbohydratesDietary FatsDiet, High-FatEatingLiverMaleRatsRats, WistarTime FactorsDietary CarbohydratesDietary Fatsendoplasmic reticuluminsulin resistanceliverproteostasissteatosis

Identifiers

PMID28851736
PMCPMC5899216
OpenAlexW2752979540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.