Evidence map›Paper›PMID 28851735›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2017

Oleate activates SREBP-1 signaling activity in

Mohamed A Lounis, Karl-F Bergeron, Maggie S Burhans, James M Ntambi, Catherine Mounier

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. [Mechanism ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
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  13. AJournal of pharmaceutical analysis · 2023
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  18. Extracellular Vesicles Secreted by TGF-Stem cells international · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Mohamed A LounisBioMed Research Center, Biological Sciences Department, University of Quebec in Montreal, Montreal, Quebec, Canada.
Karl-F BergeronBioMed Research Center, Biological Sciences Department, University of Quebec in Montreal, Montreal, Quebec, Canada.ORCID 0000-0002-7215-9104
Maggie S BurhansNutritional Sciences Department, University of Wisconsin-Madison, Madison, Wisconsin; and.
James M NtambiNutritional Sciences Department, University of Wisconsin-Madison, Madison, Wisconsin; and.
Catherine MounierBioMed Research Center, Biological Sciences Department, University of Quebec in Montreal, Montreal, Quebec, Canada; mounier.catherine@uqam.ca.
Université du Québec à Montréal · CAUniversity of Wisconsin–Madison · US

Funding

TRAINING IN NUTRITIONT32DK007665 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI GUY E GROBLEWSKI, Chi- Liang Eric Yen · 1993 to 2026
$9.2M
Role of Stearoyl-CoA Desaturase in MetabolismR01DK062388 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI NTAMBI, JAMES M. · 2002 to 2010
$2.6M
NIDDK NIH HHS R01 DK062388NIDDK NIH HHS T32 DK007665
6 · The paper itself

Abstract

Stearoyl-CoA desaturase-1 (SCD1) is a key player in lipid metabolism. SCD1 catalyzes the synthesis of monounsaturated fatty acids (MUFA). MUFA are then incorporated into triacylglycerols and phospholipids. Previous studies have shown that

Indexed as

AnimalsHepatocytesHep G2 CellsHumansLipid MetabolismLipogenesisLiverMaleMiceMice, Inbred C57BLMice, TransgenicOleic AcidSignal TransductionStearoyl-CoA DesaturaseSterol Regulatory Element Binding Protein 1Oleic AcidScd1 protein, mouseSrebf1 protein, mouseStearoyl-CoA DesaturaseSterol Regulatory Element Binding Protein 1de novo lipogenesisfatty acid protein modificationstearoyl-CoA desaturase-1sterol receptor element binding protein-1β-oxidation

Identifiers

PMID28851735
PMCPMC5814596
OpenAlexW2750955292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.