ArticlePublic health nutrition2017
Maternal pre-pregnancy BMI and offspring body composition in young adulthood: the modifying role of offspring sex and birth order.
Article in Public health nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Maternal Overnutrition in Pregnancy Predicts Greater Body Mass Index Gains in Offspring by Early Midlife: A Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Body mass index in parents and their adult offspring: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2024Pooled it
- Infancy and Childhood Obesity Grade Predicts Weight Loss in Adulthood: The ONTIME Study.Nutrients · 2021Trial
- Associations Between Maternal Pre-Pregnancy Dietary Patterns and Body Composition in Preschool Children: A Prospective Cohort Study.Nutrients · 2026Article
- Prepregnancy maternal BMI and trajectories of BMI-for-age in children up to four years of age: findings from the 2015 Pelotas (Brazil) birth cohort.International journal of obesity (2005) · 2024Article
- Parent-Offspring Associations in Body Composition: Findings From the Southampton Women's Survey Prospective Cohort Study.The Journal of clinical endocrinology and metabolism · 2023Article
- Parental body mass index and maternal gestational weight gain associations with offspring body composition in young women from the Nutritionists' Health Study.Archives of endocrinology and metabolism · 2023Article
- Gestational weight gain and visceral adiposity in adult offspring: Is there a link with the fecal abundance of Acidaminococcus genus?European journal of clinical nutrition · 2022Article
- Maternal body mass index in early pregnancy is associated with overweight and obesity in children up to 16 years of age.PloS one · 2022Article
- Animal Foetal Models of Obesity and Diabetes - From Laboratory to Clinical Settings.Frontiers in endocrinology · 2022Review
- Adherence to index-based dietary patterns in childhood and BMI trajectory during the transition to adolescence: the EPOCH study.International journal of obesity (2005) · 2021Article
- Pre-pregnancy BMI is associated with offspring body composition in adulthood before adiposity-related disorders: a retrospective cohort.Public health nutrition · 2021Article
- Influence of maternal pre-pregnancy nutritional status on offspring anthropometric measurements and body composition in three Brazilian Birth Cohorts.Public health nutrition · 2021Article
- Intergenerational Effects of Health Issues Among Women of Childbearing Age: a Review of the Recent Literature.Current nutrition reports · 2018Review
- Aerobic Exercise Preconception and During Pregnancy Enhances Oxidative Capacity in the Hindlimb Muscles of Mice Offspring.Journal of strength and conditioning research · 2018Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate if the association between maternal pre-pregnancy BMI and offspring's body composition in late adolescence and young adulthood varies by offspring birth order and sex.
designFamily cohort study, with data from registers, questionnaires and physical examinations. The main outcome under study was offspring body composition (percentage fat mass (%FM), percentage lean mass (%LM)) measured by dual-energy X-ray absorptiometry.
settingUppsala, Sweden. SUBJECTS: Two hundred and twenty-six siblings (first-born v. second-born; average age 19 and 21 years) and their mothers.
resultsIn multivariable linear regression models, maternal pre-pregnancy BMI was positively associated with daughter's %FM, with stronger estimates for first-born (β=0·97, 95 % CI 0·14, 1·80) v. second-born daughters (β=0·64, 95 % CI 0·08, 1·20). Mother's BMI before her first pregnancy was associated with her second-born daughter's body composition (β=1·05, 95 % CI 0·31, 1·79 (%FM)) Similar results albeit in the opposite direction were observed for %LM. No significant associations were found between pre-pregnancy BMI and %FM (β=0·59, 95 % CI-0·27, 1·44 first-born; β=-0·13, 95 % CI-0·77, 0·52 second-born) or %LM (β=-0·54, 95 % CI-1·37, 0·28 first-born; β=0·11, 95 % CI-0·52, 0·74 second-born) for sons.
conclusionsA higher pre-pregnancy BMI was associated with higher offspring %FM and lower offspring %LM in late adolescence and young adulthood, with stronger associations for first-born daughters. Preventing obesity at the start of women's reproductive life might reduce the risk of obesity in her offspring, particularly for daughters.
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