Evidence map›Paper›PMID 28851361›Full record

ArticleHealth and quality of life outcomes2017

Health-related quality of life of HIV infected adults with and without Visceral Leishmaniasis in Northwest Ethiopia.

Mekuriaw Alemayehu, Mamo Wubshet, Nebiyu Mesfin, Aschalew Tamiru, Abebaw Gebayehu

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Article in Health and quality of life outcomes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

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18citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  12. Tissue/Biofluid Specific Molecular Cartography ofFrontiers in cellular and infection microbiology · 2021
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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mekuriaw AlemayehuInstitute of Public Health, College of Medicine and Health Sciences, University of Gondar, P. O. Box - 196, Gondar, Ethiopia. mekuriaw14@gmail.com.
Mamo WubshetDepartment of Public Health, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Nebiyu MesfinSchool of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Aschalew TamiruLeishmaniasis Research and Treatment Center, College of Medicine and Health Sciences, University of Gondar, P. O. Box - 196, Gondar, Ethiopia.
Abebaw GebayehuInstitute of Public Health, College of Medicine and Health Sciences, University of Gondar, P. O. Box - 196, Gondar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHealth-related quality of life (HRQoL) is an important outcome measure among HIV infected patients receiving antiretroviral therapy (ART). When HIV infected patients coinfected with Visceral Leishmaniasis (VL) the problem become severe because VL accelerates HIV replication and disease progression. The impact of VL on the quality of life of HIV infected patients has not been studied. In this study in Ethiopia, we compared the quality of life of HIV infected patients with and without VL.

methodsA cross-sectional study was conducted from October 2015 to September 2016 in selected health centers and hospitals, in Northwest Ethiopia. Data on quality of life was collected by trained nurses. The instrument used to collect the data was the short Amharic version of the World Health Organization Quality of Life for HIV clients (WHOQoL-HIV). Depression was assessed using the validated version of Kessler scale. Data was entered and analyzed using SPSS version 20. Descriptive statistics, bivariate and multivariate linear regression model was used to summarize the results.

resultsA total of 590 study participants were included in the study with response rate of 95%. Of the 590 patients included in our study 125 (21%) were HIV-VL coinfection. HIV-VL coinfected patients had a lower quality of life in all the domains as compared to HIV patients without VL. Depression was consistently and strongly associated with all the quality of life domains of both groups. Also, in HIV infected patients a longer duration in ART was associated with higher HRQoL domains except for the spiritual and level of independence domains. With regard to HIV-VL coinfected patients, a longer duration in ART was associated with psychological, spiritual and level of independence domains of HRQoL. Demographics, clinical, and treatment characteristics resulted few significant associations with HRQoL domains of both groups.

conclusionHIV-VL coinfected patients had a poor quality of life in all the domains of the WHOQoL-HIV instrument. Depression, duration of ART and education were strongly associated with the quality of life. Depression should be targeted for intervention to improve the quality of life.

Indexed as

Patient Reported Outcome MeasuresQuality of LifeAdolescentAdultCase-Control StudiesCross-Sectional StudiesDepressionEthiopiaFemaleHIV InfectionsHumansLeishmaniasis, VisceralMaleYoung AdultCoinfectionHealth-related quality of lifeHuman Immunodeficiency virusVisceral Leishmaniasis

Identifiers

PMID28851361
PMCPMC5576231

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.