SynthesisBMC psychiatry2017
eHealth interventions for the prevention of depression and anxiety in the general population: a systematic review and meta-analysis.
Synthesis in BMC psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04139785 (Moodbuster, a Guided Self-help Intervention for Prevention of Depression in Primary Care), which is not on this map. Cited by 111 papers, 21 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Moodbuster, a Guided Self-help Intervention for Prevention of Depression in Primary Care
Who cites it
111 citing papers in PubMed, 21 syntheses or guidelines pooled it.
- Optimizing Workplace Digital Mental Health Interventions: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Effectiveness of digital psychological and psychoeducational interventions to prevent anxiety: Systematic review and meta-analysis of randomized controlled trials.Psychological medicine · 2025Pooled it
- Digital horizons in non-communicable disease care: a bibliometric exploration of intervention impact and innovation.Frontiers in digital health · 2025Pooled it
- Remote interventions for informal caregivers of patients with stroke: a systematic review and meta-analysis.BMJ open · 2023Pooled it
- The effectiveness of peer support for individuals with mental illness: systematic review and meta-analysis.Psychological medicine · 2023Pooled it
- eHealth-Based Psychosocial Interventions for Adults With Insomnia: Systematic Review and Meta-analysis of Randomized Controlled Trials.Journal of medical Internet research · 2023Pooled it
- Trends in Effectiveness of Organizational eHealth Interventions in Addressing Employee Mental Health: Systematic Review and Meta-analysis.Journal of medical Internet research · 2022Pooled it
- Promoting Mental Health in Parents of Young Children Using eHealth Interventions: A Systematic Review and Meta-analysis.Clinical child and family psychology review · 2022Pooled it
- Electronic Health Interventions for Patients With Breast Cancer: Systematic Review and Meta-Analyses.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2022Pooled it
- Digital Interventions for People With Co-Occurring Depression and Problematic Alcohol Use: A Systematic Review and Meta-Analysis.Alcohol and alcoholism (Oxford, Oxfordshire) · 2022Pooled it
- Cognitive behavioural therapy for anxiety in children and young people on the autism spectrum: a systematic review and meta-analysis.BMC psychology · 2021Pooled it
- Just-in-Time Adaptive Mechanisms of Popular Mobile Apps for Individuals With Depression: Systematic App Search and Literature Review.Journal of medical Internet research · 2021Pooled it
- Effect of Engagement With Digital Interventions on Mental Health Outcomes: A Systematic Review and Meta-Analysis.Frontiers in digital health · 2021Pooled it
- eHealth in the support of people with mild intellectual disability in daily life: A systematic review.Journal of applied research in intellectual disabilities : JARID · 2020Pooled it
- Psychological interventions to foster resilience in healthcare students.The Cochrane database of systematic reviews · 2020Pooled it
- Psychological interventions to foster resilience in healthcare professionals.The Cochrane database of systematic reviews · 2020Pooled it
- Telemedicine in the OECD: An umbrella review of clinical and cost-effectiveness, patient experience and implementation.PloS one · 2020Pooled it
- Rapid Review and Meta-Meta-Analysis of Self-Guided Interventions to Address Anxiety, Depression, and Stress During COVID-19 Social Distancing.Frontiers in psychology · 2020Pooled it
- Implementation Strategies to Enhance the Implementation of eHealth Programs for Patients With Chronic Illnesses: Realist Systematic Review.Journal of medical Internet research · 2019Pooled it
- Internet interventions for mental health in university students: A systematic review and meta-analysis.International journal of methods in psychiatric research · 2019Pooled it
51 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAnxiety and depression are associated with a range of adverse outcomes and represent a large global burden to individuals and health care systems. Prevention programs are an important way to avert a proportion of the burden associated with such conditions both at a clinical and subclinical level. eHealth interventions provide an opportunity to offer accessible, acceptable, easily disseminated globally low-cost interventions on a wide scale. However, the efficacy of these programs remains unclear. The aim of this study is to review and evaluate the effects of eHealth prevention interventions for anxiety and depression.
methodA systematic search was conducted on four relevant databases to identify randomized controlled trials of eHealth interventions aimed at the prevention of anxiety and depression in the general population published between 2000 and January 2016. The quality of studies was assessed and a meta-analysis was performed using pooled effect size estimates obtained from a random effects model.
resultsTen trials were included in the systematic review and meta-analysis. All studies were of sufficient quality and utilized cognitive behavioural techniques. At post-treatment, the overall mean difference between the intervention and control groups was 0.25 (95% confidence internal: 0.09, 0.41; p = 0.003) for depression outcome studies and 0.31 (95% CI: 0.10, 0.52; p = 0.004) for anxiety outcome studies, indicating a small but positive effect of the eHealth interventions. The effect sizes for universal and indicated/selective interventions were similar (0.29 and 0.25 respectively). However, there was inadequate evidence to suggest that such interventions have an effect on long-term disorder incidence rates.
conclusionsEvidence suggests that eHealth prevention interventions for anxiety and depression are associated with small but positive effects on symptom reduction. However, there is inadequate evidence on the medium to long-term effect of such interventions, and importantly, on the reduction of incidence of disorders. Further work to explore the impact of eHealth psychological interventions on long-term incidence rates.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.