SynthesisBMC medical genetics2017
Vitamin D receptor gene polymorphisms in association with diabetic nephropathy: a systematic review and meta-analysis.
Synthesis in BMC medical genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Causal insights into major risk factors for diabetic kidney disease: a comprehensive meta-analysis and Mendelian randomization study.Renal failure · 2025Pooled it
- Association of vitamin D receptor TaqI and ApaI genetic polymorphisms with nephrolithiasis and end stage renal disease: a meta-analysis.BMC medical genetics · 2019Pooled it
- Potential therapeutic impacts of vitamin D on hypothyroid-induced heart and kidney fibrosis and oxidative status in male rat.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Vitamin D deficiency and VDRFrontiers in endocrinology · 2025Article
- Nutritional Strategies against Diabetic Nephropathy: Insights from Animal Studies and Human Trials.Nutrients · 2024Review
- Potential association between arsenic and vitamin D.Frontiers in endocrinology · 2024Article
- A Mendelian randomization study on causal effects of 25(OH) vitamin D levels on diabetic nephropathy.BMC nephrology · 2023Article
- Effects of Vitamin D Receptor Genotype on Lipid Profiles and Retinopathy Risk in Type 2 Diabetes Patients: A Pilot Study.Journal of personalized medicine · 2022Article
- Article
- New susceptible locus, rs9428555, is associated with pediatric-onset immunoglobulin A nephropathy and immunoglobulin A vasculitis in Koreans.Genes & genomics · 2021Article
- Cyclin G2 regulates canonical Wnt signalling via interaction with Dapper1 to attenuate tubulointerstitial fibrosis in diabetic nephropathy.Journal of cellular and molecular medicine · 2020Article
- The Emerging Role of Vitamin D and Vitamin D Receptor in Diabetic Nephropathy.BioMed research international · 2020Review
- Arsenic exposure associated T cell proliferation, smoking, and vitamin D in Bangladeshi men and women.PloS one · 2020Observational
- Association ofBalkan journal of medical genetics : BJMG · 2019Article
- Association betweenPeerJ · 2019Article
- Cyclin G2 Suppresses Glomerulosclerosis by Regulating Canonical Wnt Signalling.BioMed research international · 2018Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA large amount of researches have demonstrated that vitamin D receptor (VDR) gene polymorphisms are associated with diabetic nephropathy (DN) risk in diabetes mellitus (DM) patients. Nevertheless, the results are inconclusive and inconsistent.
methodsWe screened PubMed, Embase, Chinese National Knowledge Infrastructure and Chinese Wanfang databases for those relevant studies updated in May 2016.
results7 studies involving 2564 subjects were recruited. We evaluated the genotypic and allelic differences between DN patients and DM controls. Overall analysis showed that no significant association was found among the ApaI, BsmI, FokI,TaqI gene polymorphisms and DN susceptibility in diabetic patients (all P values > 0.05). In the stratified analysis, TT genotype was related to DN susceptibility in Asians (TT vs Tt + tt: OR =2.21, 95% CI: 1.05-4.67, p = 0.04). The sensitivity analysis showed that the results in overall populations, Caucasians and Asians were dependable.
conclusionsNo significant association was found among the ApaI, BsmI, FokI, TaqI polymorphisms and DN risk in overall populations, the TaqI variants might related to DN susceptibility in Asians. Further researches are required to testify our meta-analysis.
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