ArticleJournal of medical virology2018
Influenza in patients with hematological malignancies: Experience at two comprehensive cancer centers.
Article in Journal of medical virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Guideline
- Corticosteroids as adjunctive therapy in the treatment of influenza.The Cochrane database of systematic reviews · 2019Pooled it
- Risk Factors for Mortality Associated With Influenza Infection in Patients With Hematologic Malignancies: A Cross-Sectional Descriptive Observational Study.Health science reports · 2026Article
- Review
- Factors influencing influenza vaccine hesitancy among cancer patients: a multicenter cross-sectional study based on the Health Belief Model.BMC infectious diseases · 2026Article
- Best Supportive Care for Patients with Chronic Lymphocytic Leukemia: Relevance of Cancer Screening and Immunizations.Cancers · 2025Review
- Outcomes and Risk Factors for Influenza and Respiratory Syncytial Virus Lower Respiratory Tract Infections and Mortality in Patients With Lymphoma or Multiple Myeloma: A 7-Year Retrospective Cohort Study.Open forum infectious diseases · 2025Article
- Antiviral Prescribing Among Patients at an Ambulatory Cancer Center With Laboratory-Confirmed Influenza.Open forum infectious diseases · 2023Article
- Nosocomial COVID-19 at a comprehensive cancer center during the first year of the pandemic: Lessons learned.American journal of infection control · 2023Article
- Clinical outcomes of coronavirus disease 2019 and seasonal influenza in patients with hematological disorders: a retrospective study.Journal of rural medicine : JRM · 2022Article
- Immune response to COVID-19 vaccination is attenuated by poor disease control and antimyeloma therapy with vaccine driven divergent T-cell response.British journal of haematology · 2022Article
- Clinical characteristics and outcomes in a cohort of oncologic patients with COVID-19 during the first year of the pandemic in Mexico.Cancer medicine · 2022Article
- Clinical Features and Risk Factors of Severe Pneumonia in Children With Acute Lymphoblastic Leukemia.Frontiers in pediatrics · 2022Article
- Chest-CT findings of COVID-19 in patients with pre-existing malignancies; a pictorial review.Clinical imaging · 2020Article
- Viral Respiratory Infections in Hematological Patients.Infectious diseases and therapy · 2020Review
- Ethical surgical triage of patients with head and neck cancer during the COVID-19 pandemic.Head & neck · 2020Review
- Influenza in patients with cancer after 2009 pandemic AH1N1: An 8-year follow-up study in Mexico.Influenza and other respiratory viruses · 2020Article
- Influenza and associated co-infections in critically ill immunosuppressed patients.Critical care (London, England) · 2019Article
- Respiratory Syncytial Virus Exceeded SARS-CoV-2 and Influenza in Lower Respiratory Infection and Mortality Rates Among Patients With Hematologic Malignancies During the 2023-2024 Respiratory Virus Season.Transplant infectious disease : an official journal of the Transplantation SocietyArticle
- Burden of Seasonal Human Coronavirus Infections in Hematopoietic Cell Transplant Recipients.Transplant infectious disease : an official journal of the Transplantation SocietyArticle
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
Abstract
The burden of influenza infections in patients with hematological malignancies (HMs) is not well defined. We describe the clinical presentation and associated outcomes of influenza at two comprehensive cancer centers (center 1 in the United States and center 2 in Mexico). Clinical and laboratory data on patients with HMs and influenza infection diagnosed from April 2009 to May 2014 at the two centers were reviewed retrospectively. A total of 190 patients were included, the majority were male (63%) with a median age of 49 years (range, 1-88 years), and had active or refractory HMs (76%). Compared to center 1, patients in center 2 were significantly sicker (active cancer, decreased albumin levels, elevated creatinine levels, or hypoxia at influenza diagnosis) and experienced higher lower respiratory tract infection (LRI) rate (42% vs 7%; P < 0.001). In multivariable logistic regression analysis (odds ratio, 95% confidence interval), leukemia, (3.09, 1.23-7.70), decreased albumin level (3.78, 1.55-9.20), hypoxia at diagnosis (14.98, 3.30-67.90), respiratory co-infection (5.87, 1.65-20.86), and corticosteroid use (2.71, 1.03-7.15) were significantly associated with LRI; and elevated creatinine level (3.33, 1.05-10.56), hypoxia at diagnosis (5.87, 1.12-30.77), and respiratory co-infection (6.30, 1.55-25.67) were significantly associated with 60 day mortality in both centers. HM patients with influenza are at high risk for serious complications such as LRI and death, especially if they are immunosuppressed. Patients with respiratory symptoms should seek prompt medical care during influenza season.
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