Evidence map›Paper›PMID 28849419›Full record

ReviewThe international journal of cardiovascular imaging2018

Myocardial T1 mapping and extracellular volume quantification: an overview of technical and biological confounders.

Stefan K Piechnik, Michael Jerosch-Herold

Erratum issuedAbstract readReview
In one paragraph

Review in The international journal of cardiovascular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Influence of hydration status on cardiovascular magnetic resonance myocardial T1 and T2 relaxation time assessment: an intraindividual study in healthy subjects.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2020
    Article
  12. Review
  13. Article
  14. Cardiovascular imaging 2018 in the International Journal of Cardiovascular Imaging.The international journal of cardiovascular imaging · 2019
    Article
  15. Article
  16. Article
  17. T1 mapping in repaired tetralogy of Fallot: A marker of fibrosis or a mirror of hemodynamics?Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Stefan K PiechnikOxford Centre for Clinical Magnetic Resonance Research, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX39DU, UK.
Michael Jerosch-HeroldBrigham and Women's Hospital, and Harvard Medical School, 15 Francis Street, Boston, MA, 02115, USA. mjerosch-herold@bwh.harvard.edu.ORCID http://orcid.org/0000-0001-9018-6731

Funding

British Heart Foundation PG/15/71/31731
6 · The paper itself

Abstract

Novel tissue biomarkers based on the spin-lattice relaxation time T1, a fundamental property in the theory of magnetic resonance physics, have emerged as a new approach for myocardial tissue characterization with many validated clinical applications. This article is intended as an overview of the physical and physiological mechanisms underlying the interpretation and the accuracy of any practical measurement of T1, or derived biomarkers such as extravascular volume fraction, and also includes a discussion of potential pitfalls. Numerous caveats und knowledge gaps related to the precise interpretation of T1-based biomarkers remain, which are being addressed incrementally through ongoing research. Equally important, further careful standardization will pave the way for a wider clinical translation of these novel T1-based biomarkers of tissue remodeling, which have been well validated for their sensitivity to pathophysiological changes, though for the most part in single-center studies.

Indexed as

Magnetic Resonance ImagingConfounding Factors, EpidemiologicExtracellular MatrixFibrosisHeart DiseasesHumansImage Interpretation, Computer-AssistedMyocardiumPredictive Value of TestsPrognosisReproducibility of ResultsVentricular RemodelingExtracellular matrixFibrosisMyocardiumRelaxationT1

Identifiers

PMID28849419
PMCPMC5851695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.