Evidence map›Paper›PMID 28849330›Full record

ArticleObesity surgery2018

Bile Gastritis Following Laparoscopic Single Anastomosis Gastric Bypass: Pilot Study to Assess Significance of Bilirubin Level in Gastric Aspirate.

Michael M Shenouda, Shady ElGhazaly Harb, Sameh A A Mikhail, Sherif M Mokhtar, Ayman M A Osman, Arsany T S Wassef, Nayer N H Rizkallah, Nader M Milad, Shady E Anis, Tamer Mohamed Nabil and 2 more

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Article in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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  15. Revisional surgery after one anastomosis/mini gastric bypass: A narrative review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2020
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Michael M ShenoudaDepartment of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt.
Shady ElGhazaly HarbDepartment of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt.
Sameh A A MikhailDepartment of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt. samehmikhail@kasralainy.edu.eg.
Sherif M MokhtarDepartment of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt.
Ayman M A OsmanDepartment of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt.
Arsany T S WassefDepartment of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt.
Nayer N H RizkallahDepartment of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt.
Nader M MiladDepartment of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt.
Shady E AnisDepartment of Histopathology, Faculty of Medicine, Cairo University, Giza, Egypt.
Tamer Mohamed NabilDepartment of Surgery, Faculty of Medicine, BeniSuef University, Benisuef, Egypt.
Nader Sh ZakiDepartment of Surgery, Faculty of Medicine, Fayoum University, Fayoum, Egypt.
Antoine HalepianDepartment of Surgery, Faculty of Medicine, Cairo University, Giza, Egypt.
Cairo University · EGBeni-Suef University · EGFayoum University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLaparoscopic single anastomosis gastric bypass (SAGB) is increasingly performed for morbidly obese patients. AIM OF WORK: This pilot study aims primarily at evaluating the incidence of bile gastritis after SAGB. The occurrence of reflux oesophagitis and reflux symptoms were also assessed. PATIENTS AND

methodsThis study included 20 patients having no reflux symptoms. All patients underwent a SAGB as a primary bariatric procedure by a single surgeon. Patients included consented to have an upper GI endoscopy done at 6 months postoperatively. Gastric aspirate was sent for bilirubin level assessment. Gastric and esophageal biopsies were submitted for histopathology and campylobacter-like organism (CLO) test.

resultsIn our study, the rate of bile gastritis was 30%. In 18 patients, the level of bilirubin in gastric aspirate seems to be related to the degree of mucosal inflammation. The remaining two patients had microscopic moderate to severe gastritis with normal aspirate bilirubin level. Two patients with bilirubin level in aspirate more than 20 mg/dl had severe oesophagitis, gastritis with erosions, and metaplasia. Relationship between bilirubin level and histopathological findings of gastric biopsy examination was statistically significant with a P value of 0.001.

conclusionThe incidence of bile gastritis in this cohort is higher than reported in the literature, and this may be worrying. The correlation between endoscopic findings and patients' symptoms is poor. Bilirubin level and pH in aspirate might be useful tools to confirm alkaline reflux. Its level might help to choose candidates for revision surgery after SAGB. This needs further validation with larger sample size.

Indexed as

AdolescentAdultBileBile RefluxBilirubinBiopsy, NeedleFemaleGastric BypassGastric MucosaGastritisHumansIncidenceLaparoscopyMaleMiddle AgedObesity, MorbidBilirubinBile gastritisBilirubin levelSingle anastomosis gastric bypass

Identifiers

PMID28849330
OpenAlexW2747930146

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.