Evidence map›Paper›PMID 28849295›Full record

Trial reportLung2017

Diet and Respiratory Health in Children from 11 Latin American Countries: Evidence from ISAAC Phase III.

Alfonso Mario Cepeda, Sumaiyya Thawer, Robert J Boyle, Sara Villalba, Rodolfo Jaller, Elmy Tapias, Ana María Segura, Rodrigo Villegas, Vanessa Garcia-Larsen, ISAAC Phase III Latin America Group

Open access · hybridAbstract readClinical Trial, Phase IIIMulticenter Study
In one paragraph

Trial report in Lung, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Integrative analysis of the intestinal metabolome of childhood asthma.The Journal of allergy and clinical immunology · 2019
    Trial
  4. Article
  5. Article
  6. Article
  7. Diet, Asthma, and Severe Asthma Exacerbations in a Prospective Study of Puerto Rican Youth.The journal of allergy and clinical immunology. In practice · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Dietary Factors Associated with Asthma Prevalence Among Children in California.Pediatric allergy, immunology, and pulmonology · 2020
    Article
  13. Article
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 4 countries.

Alfonso Mario CepedaFundación Hospital Universitario Metropolitano de Barranquilla, Barranquilla, Colombia.
Sumaiyya ThawerPopulation Health and Occupational Disease Group, NHLI Imperial College London, London, UK.
Robert J BoyleDepartment of Paediatrics, Faculty of Medicine, Imperial College London, London, UK.
Sara VillalbaFundación Hospital Universitario Metropolitano de Barranquilla, Barranquilla, Colombia.
Rodolfo JallerFundación Hospital Universitario Metropolitano de Barranquilla, Barranquilla, Colombia.
Elmy TapiasFundación Hospital Universitario Metropolitano de Barranquilla, Barranquilla, Colombia.
Ana María SeguraFundación Hospital Universitario Metropolitano de Barranquilla, Barranquilla, Colombia.
Rodrigo VillegasSchool of Public Health, University of Chile, Santiago, Chile.
Vanessa Garcia-LarsenDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe, Suite E2546, Baltimore, MD, 21205, USA. vgla@jhu.edu.ORCID 0000-0003-2713-6584
ISAAC Phase III Latin America Group
Universidad Metropolitana · COJohns Hopkins University · USImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimThe burden of childhood asthma and its risk factors is an important but neglected public health challenge in Latin America. We investigated the association between allergic symptoms and dietary intake in children from this region.

methodsAs part of the International Study of Asthma and Allergies in Childhood (ISAAC) Phase III, questionnaire collected dietary intake was investigated in relation to risk of parental/child reported current wheeze (primary outcome) and rhino-conjunctivitis and eczema. Per-country adjusted logistic regressions were performed, and combined effect sizes were calculated with meta-analyses.

results143,967 children from 11 countries had complete data. In children aged 6-7 years, current wheeze was negatively associated with higher fruit intake (adjusted odds ratio [aOR] 0.65; 95% CI 0.74, 0.97). Current rhino-conjunctivitis and eczema were statistically negatively associated with fruit intake (aOR 0.72; 95% CI 0.64, 0.82; and OR 0.64, 95% CI 0.56, 0.74, respectively). Vegetable intake was negatively associated with risk of symptoms in younger children, but these associations were attenuated in the 13-14 years old group. Fastfood/burger intake was positively associated with all three outcomes in the older children.

conclusionA higher intake of fruits and vegetables was associated with a lower prevalence of allergic symptoms in Latin American children. Conversely, intake of fastfood was positively associated with a higher prevalence of wheeze in adolescents. Improved dietary habits in children might help reduce the epidemic of allergic symptoms in Latin America. Food interventions in asthmatic children are needed to evaluate the possible public health impact of a better diet on respiratory health.

Indexed as

DietRespiratory SoundsAdolescentChildConjunctivitis, AllergicEczemaFast FoodsFemaleFruitHumansLatin AmericaMaleRhinitis, AllergicSurveys and QuestionnairesVegetablesAsthmaChildrenDietFruitsISAAC Phase IIILatin AmericaVegetablesWheeze

Identifiers

PMID28849295
PMCPMC5674121
OpenAlexW2750047070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.